去氢骆驼蓬碱肝动脉栓塞微球热解稳定性研究  

Study of harmine microspheres for hepatic arterial embolization on thermodynamics stability

作　　者：李岩[1] 孙殿甲[1] 杨永新[1] 翁幼武[1] 

机构地区：[1]新疆医科大学药学院药剂物化教研室,新疆乌鲁木齐830054

出　　处：《新疆医科大学学报》2003年第6期588-589,共2页Journal of Xinjiang Medical University

基　　金：国家西部开发专项(2000-KO1-05-02-00)

摘　　要：目的:研究盐酸去氢骆驼蓬碱明胶微球(HM—GMS)的热解动力学,初步探讨其热力学稳定性。方法:用差示热分析法(DTA)比较原料、空白做球及HM—GMS的DTA曲线,计算热解活化能、频率因子。结果:HM—GMS热解活化能为93.37 kJ/mol,频率因子平均为2.304×1013/min,说明做球可发生热解反应,但温度不高时速率较低。结论:去氢骆驼蓬碱明胶微球具有一定的热稳定性。Objective: To research the thermodynamics stability of HM-GMS. Methods: The DTA method was used to study pyrolyzation. Comparing the DTA's curve of raw material . blank microsphcres and HM-GMS, the pyrolyzative and active energy, frequency factor of HM-GMS were calculated. Results: The pyrolyzative and active energy was 93. 37 KJ/mol, frequency factor was 2. 304 × 1013/min. which showed that thermodynamics reaction could be happened of HM-GMS, but speed of this reaction was not high on low temperature. Conclusion: The thermodynamics stability of HM-GMS was available.

关 键 词：去氢骆驼蓬碱 微球 热解稳定性 差示热分析法 

分 类 号：Q949.752.6[生物学—植物学] R94[医药卫生—药剂学]