慢性肾功能不全时的低T_3、T_4综合征  

Low T_3 and T_4 Syndrome in Chronc Renal Insufficiency

作　　者：李生祺[1] 任树生[1] 王鹏[1] 张健[1] 李炜[1] 张鸿斌 张庆胜[1] 稽金芳[1] 赵世勇 刘昭[1] 杨炳贞 

机构地区：[1]天津市第三医院,300250 [2]沧州市人民医院

出　　处：《天津医药》1992年第3期150-152,共3页Tianjin Medical Journal

摘　　要：对96例慢性肾功能不全患者及52例健康对照组进行甲状腺激素测定,其中代偿期42例,失代偿期(氮质血症期)27例,尿毒症早期18例,尿毒症晚期9例。除代偿期T_3、T_4水平与对照组相比无统计学意义外,其它各期T_3、T_4水平均较对照组为低,有非常显著性差异,TSH水平各期与对照组相比无统计学意义,且患者均无甲状腺疾病症状,符合正常甲状腺功能病态综合征的表现。肾功能不全早期出现低T_3综合征,晚期出现低T_3、T_4综合征。低T_3、T_4综合征的出现可作为判断病情危重指标。Serum T_3T_4 and TSH levels in 96 cases of chronic renal insufficiency and in 52 normal adults were examined. Of them, 42 cases were of vicarious stage, 27 invicarious stage, 18 early stage of urinemia and 9 advanced stage of azotemia. All were in keeping with euthyroid sick syndrome (ESS) and without thyroid diseases.There was no statistic significance (P>0.05) in the comparison between T_3T_4 levels in vicarious stage and control group, in other stages there was significance (P<0.01). Furthermore, there was no significance statistically. When TSH levels in all stages were compared with the control group. It was shawn that low T_3 syndrome appeared in the early stage of chronic renal insufficiency, low T_3T_4 syndrome in the advanced stage of chronic renal insufficiency, It was concluded that the onset of lowT_3 T_4 syndrome might be taken as a sign in estimating the severity of the illness.

关 键 词：慢性 肾功能不全 低T3 T4 综合征 

分 类 号：R581[医药卫生—内分泌]