肺老化的HRCT评价  

Estimation of Lung Aging on High Resolution CT

作　　者：李子川[1] 黄连军[1] 曾庆玉 霍建伟 李坚 何作祥[1] 王士雯[3] 

机构地区：[1]中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院放射科,北京100037 [2]煤炭总医院放射科 [3]中国人民解放军总医院

出　　处：《中国医学影像技术》2003年第12期1629-1631,共3页Chinese Journal of Medical Imaging Technology

基　　金：973项目资助 (G2 0 0 0 0 570 0 4 )

摘　　要：目的　探讨利用高分辨率CT(HRCT)扫描来评价肺老化进程的可能性。方法　对 5 4例正常志愿者 (年龄 19～84岁 )的右肺在深吸气末与深呼气末进行上、中、下三个固定层面HRCT扫描。并对其CT值、层面面积变化率、空气滞留区及肺内微小结构改变进行观察 ,分析其是否随年龄变化。结果　呼气相平均CT值与吸气相平均CT值的差值随年龄增长其变化具有显著性差异 (P =0 .0 45 )。结论　HRCT能够提供肺老化的某些信息 ,可以做为肺老化的评价手段之一。Objective To investigate the possibility of the process of lung aging by high resolution computed tomography (HRCT). Methods 54 normal volunteers (age ranging from 19 to 84 years)were performed HRCT examination. HRCT scans were focused on the upper, mid and low parts of right lungs with the individuals holding breath in deep inspiration and deep expiration, respectively. All of the images were analyzed and compared among groups, including CT value of lungs, the variation ratios of measured lung areas between scans (inspiration and expiration), area of air trapping and the tiny lesions in lungs between different groups. Results The difference of attenuation between scans (inspiration and expiration) were significantly different with aging (P=0.045). Conclusion HRCT may show some imaging characteristic of lung aging and be a good tool for the evaluation of lung aging.

关 键 词：肺老化 HRCT扫描 形态学 评价 

分 类 号：R322.35[医药卫生—人体解剖和组织胚胎学] R814.42[医药卫生—基础医学]