1236对不孕夫妇病因探讨  

Etiological Survey of the 1236 Infertile Couples

作　　者：张翠莲[1] 张菊新[1] 高航云[1] 

机构地区：[1]河南省人民医院,河南郑州450003

出　　处：《实用妇产科杂志》2003年第6期366-368,共3页Journal of Practical Obstetrics and Gynecology

摘　　要：目的 :探讨不孕症的病因 ,从而指导临床治疗。方法 :对 12 36对不孕夫妇进行病史询问、体检及相应的辅助检查 ,对其不孕的原因进行总结分析。结果 :①单纯女方异常者 5 34对 ,占 4 3 2 0 % ;单纯男方异常者 2 5 8对 ,占2 0 87% ;双方均异常者 4 4 4对 ,占 35 92 %。②女方继发性不孕因素高于原发性不孕 ,两组差异有非常显著性 (P <0 0 1) ;男方原发不育因素高于继发组 ,差异有非常显著性 (P <0 0 1)。③女性不孕 978例中 ,排卵障碍原发不孕组高于继发组 ,差异有非常显著性 (P <0 0 1)。输卵管阻塞 5 70例 ,占 5 8 2 8% ,继发不孕组明显高于原发组 ,差异有非常显著性(P <0 0 1)。④男性不育因素 6 96例中 ,发病因素高低依次为弱精子症、少精子症、免疫学病因、男性副性腺感染。其中原发组精液异常高于继发性不育组 ;而继发性不育组男性副性腺感染、免疫学病因高于原发组。结论 :①重视生殖系统感染对不育的影响 ,且应警惕泌尿生殖系统的特殊感染。②男性因素导致的不育不容忽视。不论原发或继发不孕症 ,均应强调男女双方的检查和治疗 ,并应同步进行。③内分泌和免疫学因素对不育的影响值得进一步认识。Objective: To investigate the causing of infertile couples. Methods: Etiological survey of the 1236 infertile couples was did by inquiring the medical histories, healthy checking and relative accessory examinations. Results: ①Among the 1236 infertile couples, 534 (43.20% ) infertile couples were due to female factors, 258 ( 20.87% ) couples were due to male factors and 444 (35.92%) couples were due to both female and male factors. ②Female secondary sterile patients were significantly more than primary ones (P < 0.01). Male primary stile patients'number was significantly higher than secondary ones (P < 0.01). ③some of 978 patients were suffering ovulation obstruction and the Primary infertile number was significantly higher than secondary ones (P<0.01). 570 (58.28%) patients were suffered from fallopian tubal obstruction and the patients' number of the secondary group was significantly higher than the primary one (P<0.01). ④The factors of the 696 male infertile patients were due to abnormal sperm disease ,immune factors and infections. More patiens suffered from abnormal semen disease in the primary sterile group. Male reproductive system infection and immune factors were significantly higher in the secondary infertile group. Conclusions: ①We should pay more attention to the reproductive system infection factors in the infertile patients especially the particular infection. ②Male and female take the same role in the infertile couples and they should take the examination and treatment at the same time in order to get pregnant sooner. ③Endocrinology and immune factors also take the significant role in the sterile couples.

关 键 词：不孕夫妇 病因 治疗 辅助检查 

分 类 号：R711.6[医药卫生—妇产科学]