唾液肌酐和尿酸的酶法测定及其应用  

Analysis and application of creatinine and uric acid in saliva

作　　者：黄辉[1] 蒲晓允[1] 魏明竟[1] 王懿[1] 

机构地区：[1]第三军医大学检验系临床检验教研室,重庆400038

出　　处：《现代口腔医学杂志》2004年第1期73-74,共2页Journal of Modern Stomatology

摘　　要：目的　探讨唾液肌酐和尿酸的酶法测定及其与血清肌酐和尿酸的关系。方法　用肌氨酸氧化酶测定唾液肌酐 ,尿酸酶 -过氧化物酶法测尿酸 ,与血清肌酐和尿酸作对照分析。结果　健康人唾液肌酐和尿酸分别为 13.2 7± 5 .15 μmol/L和 10 8.2± 2 5 .4 μmol/L;唾液肌酐与血清肌酐浓度显著相关 (r =0 .88,P <0 .0 1) ,唾液尿酸与血清尿酸亦显著相关 (r=0 .5 3,P <0 .0 1)。结论　唾液肌酐浓度测定可用于慢性肾脏疾病经常性监测手段。Objective To analyze the relationship of creatinine and uric acid content between saliva and serum.Methods Creatinine content was measured by sarcosine oxidase method,uric acid was measured by uricase-peroxidase method.Enzymatic colorimetry method was used to measure the content of creatinine and uric acid in saliva.Results The content of saliva creatinine was 13.27 ± 5.15μmol/L in health,and the cotent of saliva uric acid was 108.2 ± 25.4μmol/L .There was significant relationship between saliva and plasma creatinine(r= 0.88 ,P< 0.01 ),and between saliva and plasma uric acid (r= 0.53 ,P< 0.01 ).Conclusion Saliva creatinine could be instead of serum creatinine to monitor the people of kidney disease.

关 键 词：唾液肌酐 尿酸 测定 血清肌酐 肌氨酸氧化酶 

分 类 号：R446.19[医药卫生—诊断学]