降血压食品功能因子对造模性高血压大鼠功效的研究  

Studying the Effects of Descending Blood Pressure of Hypertensive Rat With Gene of Functional Food

作　　者：韩学杰[1] 张立石[1] 王克林[1] 李涢[1] 傅妤娟[1] 王丹芳[1] 杨金生[1] 鞠大宏[1] 沈绍功[1] 王友京[2] 

机构地区：[1]中国中医研究院基础理论研究所,北京100700 [2]中国中医研究院针灸经络研究所,北京100700

出　　处：《中国中医基础医学杂志》2003年第11期24-27,共4页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：科技部 2 0 0 2基础性课题 (G 2 2 0 2 )

摘　　要：目的 :建立药物诱发的高血压大鼠模型 ;通过观察实验性高血压大鼠评价降血压食品功能因子的降压效果。方法 :应用左硝基精氨酸诱导鼠高血压模型 ,分组给予食品及药物进行干预。结果 :模型组大鼠血压出现明显稳定的升高 ,实验各组血压及生化指标有不同程度改善。结论 :药物诱发的高血压大鼠模型成功 ,降血压食品功能因子有降压作用。Objective:Prepared the hypertensive model,To observe effects of descending Blood Pressure of Hypertensive Rat with Gene of Functional Food (Roots of Kudzu Vine and Leafs of Ginkgo) in blood pressure and indications of biochemistry.Methods:Injected L-NNA into the abdomen of Rats to settle the hypertensive model.Then Roots of Kudzu Vine and Leafs of Ginkgo as well as Traditional Chinese medicine were used to treat them for 4 weeks.Results:The blood pressure of model group was ascending.The blood pressure of other groups were descending and indications of biochemistry had changed.Conclusion:The Blood Pressure of model gorup were ascending after 4 week.Functional Food can descending Blood Pressure and changing indications of biochemistry.

关 键 词：降血压食品功能因子 高血压 大鼠 左硝基精氨酸 银杏叶片 葛根制剂 

分 类 号：R285.5[医药卫生—中药学] R259.441[医药卫生—中医学]