不育男性精子密度、活动率、活力与顶体酶活性关系的研究  

Relationship between sperm concentration, vitality, motility and sperm acrosin activity in infertile patients

作　　者：刘睿智[1] 王忠山[1] 许宗革[1] 路英丽[1] 沙艳伟[1] 辛暨丽[1] 

机构地区：[1]吉林大学基础医学院细胞生物学教研室,长春130021

出　　处：《中国男科学杂志》2003年第6期376-377,386,共3页Chinese Journal of Andrology

基　　金：吉林省计划委员会资助项目(1999)

摘　　要：目的 探讨不育男性精子密度、活动率、活力、与精子顶体酶活性的关系。方法 采用分光光度比色法测定精子顶体酶活性,并将其与精子密度、活动率和活力进行统计分析。结果随着精子密度、活动率、活力降低、精子顶体酶活性均明显降低(各组间比较均P<0.001)。结论 不育男性精子顶体酶活性降低可影响精子密度、活动率和a、b级活力精子率,精子顶体酶活性可作为男性不育精子质量检测的指标之一。Objective To study the relationship between sperm concentration, vitality, a, b grade motile sperm concentration and sperm acrosin activity in infertile patients. Methods Semen analysis and sperm acrosin activity were measured and analyzed in 3580 infertile men. Results The results showed that the acrosin activity significantly decreased when sperm concentration, vitality, a, b grade motile sperm concentration significantly decreased(P <0. 001 ). Conclusion The sperm acrosin activity influences the sperm concentration, vitality, a, b grade motile sperm concentration, so it should be the first and practical selection for assessing male fertility potential.

关 键 词：男性不育 精液分析 顶体酶 男性 精子 

分 类 号：R698.2[医药卫生—泌尿科学]