NPY-IR纤维在大鼠心肌内的分布和密度  

The Distribution and Density of NPY-IR Fibers in Working Myocardium of Rat

作　　者：张云芳[1] 赵玲辉[1] 刘慧冬[1] 李益民[1] 李晓冬[1] 李玉兰[1] 

机构地区：[1]哈尔滨医科大学解剖学教研室,黑龙江哈尔滨150086

出　　处：《解剖科学进展》2003年第4期317-318,320,共3页Progress of Anatomical Sciences

摘　　要：目的　观察NPY IR纤维在大鼠工作心肌的分布和密度 ,为心脏的生理和病理学研究提供形态学基础。方法　用免疫组织化学方法显示大鼠工作心肌内的NPY IR纤维 ,用电子表格Excel 2 0 0 0计算其分布密度。结果　在心房肌内和心室肌内均可见NPY IR阳性纤维 ,心房肌内NPY IR纤维的面积密度和数密度均高于心室肌。结论　NPY IR纤维在大鼠心肌内分布广泛 ,其分布密度存在部位差异。Objective To study the distribution and density of neuropeptide Y immunoreactive (NPY-IR) fibers in working myocardium of rat and provide the morphological base for the study in physiology and pathology of heart. Methods The immunohistochemical staining was used to show the positive fibers of NPY-IR and the Excel 2000 was used to calculate the density of NPY-IR fibers in myocardium of rat. Results NPY-IR positive fibers were found in both atrium myocardium and ventricle myocardium with deep brown positive staining fibers as fine terminal fibers scattered among working myocardium. The density of NPY-IR positive fibers in atrium myocardium is higher than that in ventricle myocardium. Conclusion NPY-IR fibers exist in both atrium and ventricle myocardium and the density of the fibers is different in different part of the myocardium of the working heart in rat.

关 键 词：NPY-IR纤维 大鼠 心肌 分布 密度 

分 类 号：R322.1[医药卫生—人体解剖和组织胚胎学]