血浆蛋白对生物材料细菌粘附影响研究进展  

Advances of influence of plasma proteins on bacterial adhesion to bioma terials

作　　者：李艳星 黄云超[2] 熊素华 

机构地区：[1]湖南省衡阳市中心医院胸心外科,湖南衡阳421001 [2]昆明医学院第二附属医院胸心外科,云南昆明650101

出　　处：《国外医学（生物医学工程分册）》2003年第6期268-272,共5页Foreign Medical Sciences(Biomedical Engineering Fascicle)

基　　金：云南省应用基础研究基金资助项目(2000C0110M);云南省教委科研基金资助项目(9912206);云南省中青年后备人才培养基金资助项目(2000YP10)

摘　　要：防止生物材料细菌粘附是防治生物材料为中心感染(biomaterialcenteredinfect,BCI)的重要环节。研究发现,人体血浆蛋白对生物材料细菌粘附有重要影响。因此,研究血浆蛋白与生物材料细菌粘附关系为防治BCI有重要的意义。本文综述了与生物材料细菌粘附相关的血浆蛋白、血浆蛋白对生物材料细菌粘附影响的有关机制及如何提高血浆蛋白抗细菌粘附作用的展望。Preventing bacterial adherence to biomaterials has been identified as a n important step to prevent Biomaterial Centered Infect (BCI).People find tha t human plasma proteins have important influence on bacterial abhesion to biom aterials.Thus,researching the relevant relations both the plasma proteins an d bacterial adhesion to biomaterials has important meaning to prevent BCI.In this article,we review some relevant plasma proteins related to bacterial a dhesion to biomaterials,and relevant mechanism which human plasma proteins af fect bacterial adhesion to biomaterials and prospects how to improve the usage o f anti-bacterial adhesion of human plasma proteins.

关 键 词：血浆蛋白 细菌 生物材料 表面粘附 

分 类 号：R318.08[医药卫生—生物医学工程]