正心泰对急性心肌梗死患者左心室功能及心室晚电位的影响  

Effect of treatment with Zhengxintai(正心泰) on left ventricular function and late potential in patients with acute myocardial infarction

作　　者：郑晓明[1] 刘雪梅[2] 李晓青[2] 李彤华[1] 张艳丽[2] 郝冰[1] 

机构地区：[1]河北省唐山市开滦医院心内科,河北唐山063000 [2]河北省唐山市开滦医院功能科,河北唐山063000

出　　处：《中国中西医结合急救杂志》2003年第6期356-358,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：河北省科委指令性课题 ( 0 12 76175 D)

摘　　要：目的 :探讨正心泰治疗急性心肌梗死 (AMI)的电生理机制。方法 :将 5 9例 AMI患者按随机法分为观察组及对照组 ,分别接受常规西药加正心泰及单纯西药治疗 ,以超声心动图及晚电位检测仪检查治疗后患者的左心室功能和心室晚电位 (VL P)各项指标变化。结果 :治疗后观察组左心功能各项指标均明显优于对照组(P均 <0 .0 5 ) ;观察组的 VL P阴性率 (2 6 % )明显低于对照组 (18% ,χ2 =4 .71,P<0 .0 5 ) ,VL P各指标也明显好于对照组 (P<0 .0 5或 P<0 .0 1)。结论 :正心泰可改善 AMI患者左心室功能 ,并降低心室晚电位阳性率。Objective:To study the electrophysiologic mechanism of Zhengxintai(正心泰) in treatment of acute myocardial infarction (AMI).Methods:The 59 patients with AMI were randomly divided into treatment group (treatment with western medicine and Zhengxintai ) and control group (treatment with ordinary western medicine ).The indexes of left ventricular function and late potential(VLP) were examined by the echocardiogram(ECG) and the ECG workstation.Results:Every indexes of treatment group after treatment were significantly better than those in control group (all P<0.05). The negative rate (26 percent) of VLP in treatment group was lower markedly than that in control group (18 percent, χ2=4.71, P<0.05), and the others indexes of VLP were superior to control group (P<0.05 or P<0.01). Conclusion:Zhengxintai may ameliorate left ventricular function and reduce the positive rate of late potential of AMI patients.

关 键 词：正心泰 急性心肌梗死 左心室功能 心室晚电位 电生理机制 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]