大连和沈阳两市区79例母乳中二噁英污染水平调查  

A survey on the dioxin level in breast milk in coastal and inland region

作　　者：金一和[1] 陈慧池 唐慧君[3] 金秀花 刘惠芳[3] 李珍[3] 香山不二雄 滨松昌彦 匂坂馨 David Brown George Clark 中村昌文 

机构地区：[1]中国医科大学公共卫生学院卫生毒理学教研室,沈阳110001 [2]中国医科大学第二附属医院妇产科 [3]大连医科大学第二附属医院妇产科 [4]日本自治医科大学 [5]日本东京都监察医务院 [6]Xenobiotic Detection System International [7]日本日吉株式会社

出　　处：《中华预防医学杂志》2003年第6期439-441,共3页Chinese Journal of Preventive Medicine

摘　　要：目的　通过测定乳汁中二英类污染物浓度 ,了解我国人群体内二英负荷水平 ,对新生儿授乳期间的二英每日摄入量进行卫生学评价。方法　采用CALUX生物法测定内陆城市 (沈阳地区 32例 )和沿海城市 (大连地区 4 7例 )初产妇乳汁中二英总毒性当量。结果　大连地区母乳中二英类污染物总毒性当量中位数为 15 84 73pgTEQs/gfat,显著高于沈阳地区 7 2 12 9pgTEQs/gfat。 结论　我国母乳中二英污染水平处于世界平均水平 ,新生儿授乳期间二英摄入量估计值超过WHO推荐的成人每日耐受量 ,应该引起相关部门足够的重视。Objective To study the dioxin level of breast milk among Chinese mothers,and to assess the dioxin intake of new-born babies from mother’s milk and compare with the Tolerable Daily Intake(TDI)of dioxin. Methods The CALUX bioassay was used to detect the dioxin concentration of the first time mother’s milk among the inland samples (Shenyang region; 32 cases) and the coastal city samples (Dalian region; 47 cases). Results The median value of the dioxin Toxic Equivalence (TEQ) in breast milk in the Dalian region was 15.84 pg TEQs·g-1 fat,which was significantly higher than that in the Shenyang region 7.21 pg TEQs·g -1 fat (P<0.01).Conclusion The dioxin level in breast milk in Chinese is at the world's average level.The dioxin intake of the new-born babies during the period of lactation was higher than the lowest limit of the Tolerable Daily Intake (TDI) proposed by WHO.This situation should be noticed by the related authorities.

关 键 词：大连市 沈阳市 母乳 二噁英污染 调查 毒性 新生儿 

分 类 号：R174[医药卫生—妇幼卫生保健]