扶阳救心滴丸对大鼠急性心肌缺血的保护作用  

Protective Effect of FJDP on Acute Myocardial Ischemia in Rats

作　　者：胡冰[1] 于晓凤[1] 曲绍春[1] 徐华丽[1] 睢大员[1] 

机构地区：[1]吉林大学药学院药理学教研室,吉林长春130021

出　　处：《吉林大学学报（医学版）》2003年第6期777-779,共3页Journal of Jilin University：Medicine Edition

摘　　要：目的 :观察扶阳救心滴丸 ( FJDP)对大鼠急性心肌缺血的保护作用。方法 :建立垂体后叶素 ( Nh)致急性心肌缺血及冠状动脉结扎致急性心肌梗塞模型 ,采用心电图机测定 FJDP对大鼠 导联及胸 V1 导联心电图变化的影响。结果 :FJDP 30和 60 mg· kg-1 对 Nh诱发大鼠心电图 T波及 ST段的抬高有明显降低作用 ,亦能明显改善冠状动脉结扎致心肌梗塞不同时间点的缺血性心电图变化。结论Objective:To observe protective effect of fuyangjiuxin dripping pills (FJDP) on acute myocardial ischemia in rats. Methods:In models of acute myocardial ischemia induced by neurohypo physeal hormone (Nh) and myocardial infarction caused by ligating coronary artery,the effect of FJDP on ECG in acute myocardial ischemia rats was observed. Results:FJDP could reduce the heights of ST segment and T wave which were caused by injecting Nh and ligating coronary artery. Conclusion:FJDP can obviously improve the ECG of rats with acute myocardial ischemic.

关 键 词：扶阳救心滴丸 心肌缺血 心肌梗塞 心电描记术 大鼠 WISTAR 保护作用 

分 类 号：R542.2[医药卫生—心血管疾病] R965[医药卫生—内科学]