377株大肠埃希菌的耐药性分析  

Analysis on the antibiotic resistance of 377 strains of Escherichia coli

作　　者：张中奎[1] 解晓珍[1] 石云[1] 

机构地区：[1]第三军医大学新桥医院检验科,重庆400037

出　　处：《重庆医学》2003年第12期1621-1623,共3页Chongqing medicine

摘　　要：目的　分析本院大肠埃希菌感染的耐药状况 ,为临床合理使用抗生素提供可靠的实验依据。方法　收集本院 1 999年 1月～ 2 0 0 2年 1 2月 4年间各种临床标本中分离的大肠埃希菌 377株 ,应用API细菌鉴定系统进行鉴定 ,并用K B法进行药敏实验。结果　大肠埃希菌对泰能、哌拉西林 /三唑巴坦、呋喃妥因、头孢他定、阿米卡星敏感 ,耐药率分别为 7.2 0 %、1 0 .83%、1 4 .70 %、1 6 .6 2 %、1 8.6 5 % ,对阿莫西林、哌拉西林、复方新诺明、氨苄西林的耐药率均 >70 %。结论　大肠埃希菌是引起各类临床感染的重要病原菌之一 ,临床应结合药敏结果合理使用抗生素 ,以提高对该菌的有效控制 。Objective To investigate the antibiotic resistance of Escherichia coli(E.coli) in Xinqiao Hospital and provide the credible antimicrobial susceptibility test(ATB) results for clinical antibiotic use.Methods A total of 377 clinical isolates of E.coli were collected from different districts of Xinqiao Hospital from January 1999 to December 2002.Bacteria were identified with API system.K B methods were performed to detect the drug resistances of these strains.Results E.coli was sensitive to imipenem,piperacillin tazobactam,nitrofurantoin,ceftazidime,amikacin and the antibiotic resistance was 7.20%,10.83%,14.70%,16.62%,18.65%,respectively.E.coli was resistant to amoxicillin,piperacillin,trimethoprim/sulfa,ampicillin and the antibiotic resistances were all above 70%.Conclusion E.coli is one of the important pathogens that cause extensive clinical infections.Clinical antibiotic use should accord to the AST results.

关 键 词：大肠埃希菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学]