时间平均尿素浓度在预测血液透析间期心力衰竭中的价值  

Clinical Study of Time-average Concentration of urea in Forecasting the Heart Failure in Interhemodialysis

作　　者：关晓东[1] 吴宇芳[2] 赵文[1] 李光绍[3] 

机构地区：[1]广东省东莞东华医院肾内科,523013 [2]广东省东莞东华医院检验科,523013 [3]广东省东莞东华医院心内科,523013

出　　处：《中国误诊学杂志》2003年第12期1792-1794,共3页Chinese Journal of Misdiagnostics

基　　金：东莞市 2 0 0 2年度科技进步三等奖 (项目编号 :2 0 0 2 4 3)

摘　　要：目的 :探讨时间平均尿素浓度 (Time- average Concentration of urea TACurea)在预测血液透析间期 (IHD)心力衰竭 (HF)中的临床价值。方法 :以 TACurea作为评价血液透析 (HD)充分性的客观指标 ,对 82例维持性血液透析(MHD)患者于 IHD发生 HF进行分析。结果 :MHD82例于 9986例次 IHD中发生 HF2 2 9例次 (2 .2 9% ) ,主要原因依次是 HD不充分、感染、高血压控制不良、贫血未纠正。HF组平均 TACurea为 (2 4 .6± 4 .5 ) mmol/ L,表明 TACurea≥ (2 4 .6± 4 .5 ) mmol/ L 易并发 MHD间期 HF。结论 :HD不充分是诱发 HD间期 HF的最主要因素 ,TACurea可以作为 MHD间期 HF的预测指标。Objective:To investigate the clinical significance of Time-average concentration of urea(TACurea) in forecasting the heartfailure (HF) in interhemodialysis(IHD).Methods:TACurea was used as the reference method, 82 cases patients with maintenancehemodialysis who induced HF in IHD were analysed.Results:The incident of HF in IHD was 2.29%.The major factors successively were incomplete HD,infection, blood pressure uncontrol, severe anemia and water-sodium overload. The average TACurea level of HF groups was (24.6±4.5) mmol/L. It indicated that TACurea higher than (24.6±4.5) mmol/l would induced HF easily in IHD. Conclusion:In complete HD was the major factor who would induce HF in IHD.TACurea would be used as the index of forecasting the HF in IHD.

关 键 词：尿素分析 预测 肾透析 心力衰竭 充血性/诊断 

分 类 号：R541.61[医药卫生—心血管疾病]