DTI-DSE检出家猪慢性冬眠心肌的价值  

The Value of Doppler Tissue Imaging Combining Dobutamine Stress Echocardiography in Detecting Chronic Hibernating Myocardium(CHM) in Pigs

作　　者：朱红[1] 李东野[1] 夏勇[1] 潘德峰[1] 杨煜[1] 李雷[1] 史春志[1] 陈静[1] 祁春梅[1] 

机构地区：[1]徐州医学院附属医院心内科,江苏221002

出　　处：《齐齐哈尔医学院学报》2003年第12期1333-1334,共2页Journal of Qiqihar Medical University

基　　金：江苏省应用基础研究项目资助 (编号BJ2 0 0 0 0 59)

摘　　要：目的　评价多普勒组织成像技术结合多巴酚丁胺超声负荷试验 (DTI -DSE)检出慢性冬眠心肌 (CHM )的价值。方法　制备成家猪慢性冬眠心肌及心肌梗死的模型后行DTI -DSE ,分别于静息状态 ,小剂量多巴酚丁胺 (Dob)时观察左室壁的收缩期运动峰值速度 (Vs)。比较正常心肌节段(NM )、慢性冬眠心肌节段、心肌梗死节段 (MI)的Vs、心肌收缩期运动峰值速度变化率 (△Vs)。结果　三种心肌节段的Vs、△Vs均为NM >CHM >MI。结论　DTIObjective To evaluate the value of Doppler tissue imaging(DTI)combining Dobutamine stress echocardiography(DSE)in detecting chronic hibernating myocardium(CHM).Methods Animal models of CHM and myocardial infarction(MI) in domestic Chinese pigs were established . Combining DSE and DTI ,observing the peak velocity of left ventricle wall in systolic period (Vs) at rest and with dobutamine 10ug·kg -1 ·min -1 Comparing the Vs and variety ratio(△Vs ) of three kinds of myocardial segments :normal myocardial (NM)segments 、CHM segments and MI segments .Results Vs of NM>Vs of CHM>Vs of MI at rest and with dobutamine 10ug·kg -1 ·min -1 . △Vs of NM>△Vs of CHM>△Vs of MI .Conclusions DTI-DSE is a quantify index in detecting CHM.

关 键 词：DTI-DSE 家猪 慢性冬眠心肌 动物模型 多巴酚丁胺 多普勒组织成像技术 超微结构 

分 类 号：R542.2[医药卫生—心血管疾病] R445.1[医药卫生—内科学]