The Change of Serum Prolactin Level after Multiple Injection of Norethisterone Enanthate and Estradiol Valerate  

作　　者：吴振宇 邵庆翔 桑国卫 

机构地区：[1]InstituteofFamilyPlanningResearch,ZhejiangAcademyofMedicine,Hangzhou310013,Zhejiang,China

出　　处：《Journal of Reproduction and Contraception》1991年第2期44-48,共5页生殖与避孕（英文版）

摘　　要：Sixteen healthy fertile women were recruited in a longitudinal study,and monthly given an injectable containing Norethisterone Enanthate (NET-EN) 50mg and Estradiol Valerate (EV) 5mg on the 5th day of menstrual cycle for 12 months.Blood samples were collected from each subject prior to and on day 1,7,21 after the 1st,6th and 12th injection.Serum Prolactin (PRL) level was measured by RIA.The PRL level of each cycle in almost every individual showed an obvious increase after injection of NET-EN/EV,followed by a gradual decrease from the middle of cycle length,then returned to its basal level.The profile of PRL level for each treated cycle could be well described by polynomial equation.The results indicate that there is no obvious effects and constant increase tendency on PRL level after long-term (1 year) injections of NET-EN 50mg/EV 5mg in healthy women.

关 键 词：炔诺酮庚酸盐 雌二醇戊酸酯 血清 泌乳刺激素 避孕 

分 类 号：R979.21[医药卫生—药品]