美解眠介入脑血流显像对癫痫病灶的定位研究  

Bemegride Evoked Subclinicalictal Brain Blood Imaging For Localization of Epileptic foci

作　　者：宋文忠[1] 陈明曦[1] 何永生[1] 蒋万书[1] 曹开文[1] 

机构地区：[1]四川省人民医院校医学科

出　　处：《中国医学计算机成像杂志》1995年第4期236-238,共3页Chinese Computed Medical Imaging

摘　　要：目的：研究美解介入ＳＰＥＣＴ脑血流显像对癫痫病灶的定位。材料和方法：将药物诱发脑电图技术与９９ｍＴｃ－ＥＣＤＳＰＥＣＴ脑血流显像相结合建立美解眠介入亚临床发作脑血流显像并对１４例局限性癫痫患者（８例经外科手术切除癫痫病灶）进行了发作间期和亚临床发作期脑血流显像比较研究。结果：亚临床发作期癫痫病灶脑血流平均较间期增加１２．６５％。１０／１４例增加超过５％，８／１４例增加超过１０％，最多增加超过３１％。图像比较以亚临床发作期病灶血流出现反转和填充较有意义。结论：本方法可克服发作期显像不易及时注入显像剂的缺陷。Purpose: To study the SPECT brain blood imaging with intervention of bewegride for localization of epileptic foci. Materials and Methods: Drug evoked EEG was combined with 99mTc-ECDSPECT brain blood imaging to establish subclinicalictal brain blood imaging. 14 patients with partial epilepsy(M8 F6, age 13-46 y. 8 cases had been operated to resect epileptic foci) had been studied using99mTc-ECD SPECT in interical and subclinicalictal status. Results: The mean elevation of blood flow of epileptic foci in subclinicalictal state was about 12.65% comparison to interictal state. 10/14 cases increased more than 5%,8/14 more than 10%, the most increased case was about 31%. The reversed and filling perfusion images in subclinicalictal state may be valuable for localization of epileptic foci. Conclusion: The drug evoked subclinicalictal imaging can be carried out at any time easily and safely.

关 键 词：SPECT脑血流显像 癫痫 病灶 药物诱发脑电图技术 亚临床发作期 药物介入 美解眠诱发试验 

分 类 号：R814.42[医药卫生—影像医学与核医学] R742.1[医药卫生—放射医学]