硝酸甘油介入心肌显像检测存活心肌  

Identification of Viable Myocardium in Tc-99m-MIBI Imaging by Sublinglial Nitrate

作　　者：黄钢[1] 单越芬[1] 曾骏[1] 孙晓光[1] 刘文官[1] 赵惠扬[1] 陈可靖[1] 

机构地区：[1]上海医科大学附属中山医院核医学研究室

出　　处：《中国医学计算机成像杂志》1995年第4期247-250,共4页Chinese Computed Medical Imaging

摘　　要：目的：观察硝酸甘油介入对常规静息心肌显像异常减低区存活心肌判断的作用。材料和方法：２８例冠心病患者在一周内进行了Ｔｃ－９９ｍ－ＭＩＢＩ常规静息心肌显像及含服硝酸甘油后心肌显像。结果：在１４４个常规静息心肌显像中的放射性异常减低区段，有６１个（４２的）区段在含服硝酸甘油后显像见局部Ｔｃ－９９ｍ－ＭＩＢＩ摄取明显增加，其中２３个区段局部放射性分布计分上升２级；同时硝酸甘油心肌显像明显提高心／肝及心／肺比值，改善了图像质量。结论：硝酸甘油介入后Ｔｃ－９９ｍ－ＭＩＢＩ心肌显像明确提高了常规静息心肌显像对存活心肌判断的灵敏性。Purpose: This study investigated the role of sublingual nitrate Tc-99m-MIBI imaging on detecting viable myocardium in the defects by routine resting Tc-99m-MIBI imaging. Materials and Methods: 28 patients with coronary artery disease underwent myocardial tomography with Tc -99m-MIBI at rest(R)and after the administration of sublingual nitrate(N) were analyzed.Resluts: Of 144 myocardial segments with defect on routine resting imaging, 61(42%) demonstrated remarkably enhanced uptake of Tc-99m-MIBI after administration of sublingual nitrate. Meanwhile, the quality of N imaging was improved because of the increasing ratio of myocardium/lung and myocardium/liver perfusions. Conclusion: Sublingual nitrates before Tc-99 m-MIBI injection do improve sensitivity of Tc-99m-MIBI myocardial imaging for detecting viable myocardium.

关 键 词：硝酸甘油介入心肌显像 存活心肌 冠心病 心肌缺血 

分 类 号：R816.2[医药卫生—放射医学] R541.4[医药卫生—临床医学]