Wistar大鼠运动皮层代表区的微刺激测定  

Microstimulation Mapping of the Motor CorticalRepresentations in Wistar Rats

作　　者：恽君惕[1] 李斌[1] 房鑫[1] 顾晓蓬[1] 

机构地区：[1]中国协和医科大学基础医学院

出　　处：《中国实验动物学报》1995年第1期20-23,共4页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家自然科学基金

摘　　要：在１５例氯胺酮麻醉的Ｗｉｓｔａｒ大鼠利用皮层内微刺激技术测定了躯体的运动皮层代表区。电刺激为３５０Ｈｚ的阴极串脉冲，电流最大值限为８０μＡ。结果表明大多数皮层点诱发对侧肌肉反应。虽然代表区的大小有很大个体差异，分区的相对位置是恒定的。但在分区内部未见分域排列。部分大鼠存在前部前肢区，但无一例发现前部后肢区。比较文献结果提示Ｗｉｓｔａｒ大鼠的运动皮层的分化程度比Ｌｏｎｇ－Ｅｖａｎｓ黑顶鼠低。otor cortical representations of the body parts in 15 Wistar rats weredetermined using intracortical microstimulation technique under ketamineanaesthesia. The stimulus parameters were a train of 0.25ms cathodal pul-ses at 350Hz with the maximum current of 80A. The results showed thatthe great majority of evoked muscular responses were contralateral. Altho-ugh there was considerable variability in the size of the representationalmaps between the subjects, tha relative location of subdivisions was const-ant. Within the subdivisioas ( such as riorelimb area ) , however, no topo-graphical arrangement was evident. In soine rats roustral forelimb areasdid exist but none were roustral hindlimb areas found. Comparison of ourresults with those in the literature suggests that the motor cortex of theWistar rat is less specialized than that of Long-Evans hooded rats.

关 键 词：大鼠 运动皮层 微刺激 神经元 

分 类 号：Q42[生物学—神经生物学] Q95-33[生物学—生理学]