Transcatheter closure of ventricular septal defect in patients with aortic valve prolapse and mild aortic regurgitation:feasibility and preliminary outcome  

作　　者：Guan-Liang Chen Hai-Tao Li Hai-Rong Li Zhi-Wei Zhang 

机构地区：[1]Zhujiang Hospital Affiliated to Southern Medical University [2]Department of Pediatric Cardiology,Guangdong Cardiovascular Institute,Guangdong Academy of Medical Science,Guangdong General Hospital [3]Department of Cardiology,Hainan General Hospital

出　　处：《Asian Pacific Journal of Tropical Medicine》2015年第4期315-318,共4页亚太热带医药杂志（英文版）

基　　金：supported by National Nature Science Foundation of China(NO.81260052);Science and Technology Planning Project of Hainan Province of China(NO.812147)

摘　　要：Objective:To evaluate the feasibility,safety and efficacy of transcathcter closure of ventricular septal defect(VSD)in patients with aortic valve prolapse(AVP)and mild aortic regurgitation(AR).Methods:Between January 2008 and July 2014,transcatheter closure of VSD was attempted in 65 patients.Results:The total intermediate closure successful rate in all subjects was 96.9%.During the perioperative period,no death,major bleeding,pericardial tamponade,occluder dislodgement,residual shunt or hemolysis occurred.Two procedures had been forced to suspend due to significant aggregation of device related aortic regurgitation,three cases of transient complete left bundle branch block occurred but did not sustain.At 1-year followup,no patients had residual shunts and complications.Furthermore,grade of residual AR were relieved in 61.9%(39/63)cases and degree of AVP were ameliorated in 36.5%(23/63)patients;Conclusions:Transcatheter closure VSD in selected patients with AVP and mild AR is technically feasible and highly effective.Long term safety and efficacy needs to be assessed.Objective:To evaluate the feasibility,safety and efficacy of transcathcter closure of ventricular septal defect(VSD)in patients with aortic valve prolapse(AVP)and mild aortic regurgitation(AR).Methods:Between January 2008 and July 2014,transcatheter closure of VSD was attempted in 65 patients.Results:The total intermediate closure successful rate in all subjects was 96.9%.During the perioperative period,no death,major bleeding,pericardial tamponade,occluder dislodgement,residual shunt or hemolysis occurred.Two procedures had been forced to suspend due to significant aggregation of device related aortic regurgitation,three cases of transient complete left bundle branch block occurred but did not sustain.At 1-year followup,no patients had residual shunts and complications.Furthermore,grade of residual AR were relieved in 61.9%(39/63)cases and degree of AVP were ameliorated in 36.5%(23/63)patients;Conclusions:Transcatheter closure VSD in selected patients with AVP and mild AR is technically feasible and highly effective.Long term safety and efficacy needs to be assessed.

关 键 词：TRANSCATHETER closure VENTRICULAR SEPTAL defect AORTIC valve prolapsed AORTIC REGURGITATION 

分 类 号：R654.2[医药卫生—外科学]