肾脏疾病患儿尿选择性蛋白电泳测定的临床应用评价  

CLINICAL APPLICATION OF URINARY PROTEIN ELECTROPHORESIS DETECTION IN CHILDREN WITH GLOMERULOPATHY

作　　者：管立学[1] 赵中珩 周立忠[1] 李廷孝[1] 马居风[1] 倪光臻[1] 

机构地区：[1]潍坊市人民医院检验科

出　　处：《潍坊医学院学报》1992年第2期102-104,共3页Acta Academiae Medicinae Weifang

摘　　要：报告了149例肾脏疾病患儿尿蛋白定性与尿蛋白电泳结果。18例急性肾小球肾炎患儿均为选择性蛋白尿;肾病组88例选择性蛋白尿占59.1％,非选择性蛋白尿占40.9％,定性“++”非选择性蛋白尿约占24.1％(7/29);肾病综合征患儿以非选择性蛋白尿为主,占56.7％,紫癜性肾炎患儿13例中84.6％为高度选择性蛋白尿。所有病例尿蛋白定性“±～+”者均为高度选择性蛋白尿,定性“++～+++”者与非选择性蛋白尿例数呈正相关,r=0.926,y=25x-19.1。The results of detecting urinary protein electrophoresis in a variety of glomerulopathy in children were reported in this article, by using direct electrophoresis on cellulose acetate membranes for fresh-urine. 149 urinarg samples of the patients were analyzed. In 18 patients with acute glomerulopathy, the urinary proteins showed on electrophoretograms were all selected, nearly 100%. The selective protein urines constituted about 59.1%, in 88 patients with nephropathy, non-selected protein urines were about 40.9%. In 30 patients with nephritic syndrome, the rates of non-selected protein urines increated, it was about 56.7%. It was mainly high selected protein urines, about 84.6%, that the urines in children with focal glomeruloselerosis. Correlation between the rates of non-selected protein urines(y) and the number of determined urinary protein≥++(x) yielded the following results: y=25x-19.1, r=0.926, n=103.

关 键 词：肾病 尿蛋白电泳 儿童 

分 类 号：R726.920.4[医药卫生—儿科]