肝移植术后肺部真菌感染11例临床分析  

Clinical analysis of 11 cases with pulmonary fungal infection after liver transplantation

作　　者：陈建斌[1] 魏思东[1] 陈国勇[1] 孙建军[1] 汤高枫[1] 袁振华[1] 

机构地区：[1]郑州人民医院肝胆胰外科,河南郑州450053

出　　处：《实用器官移植电子杂志》2015年第6期358-360,共3页Practical Journal of Organ Transplantation(Electronic Version)

基　　金：国家自然科学基金项目(81370577)

摘　　要：目的探讨肝移植术后肺部真菌感染的临床特点、诊断及治疗措施。方法回顾性分析了74例2013年10月至2014年10月在郑州人民医院肝移植术后出现肺部真菌感染的11例患者的临床资料,采取个体化的治疗和管理,并对临床数据进行总结分析。结果在74例肝移植病例中,肺部真菌感染受者占14.9%(11/74)。11例肝移植术后肺部真菌感染患者中,8例治愈,治愈率为72.7%;3例死亡,病死率为27.3%。结论肝移植术后肺部真菌感染的患者均无典型的临床特点,容易干扰临床诊断,应引起肝移植中心医师的足够重视,尽早鉴定菌种并根据药敏试验使用敏感抗菌药物是成功救治肝移植术后肺部真菌感染的关键。Objective To investigate clinical feature, diagnosis, and treatment of pulmonary fungal infection after liver transplantation.Methods This is a retrospective analysis of the clinical data of11 patients who underwent pulmonary fungal infections after liver transplantation from October2013 to October2014 in Zhengzhou People''s Hospital. The patients appeared to take individualized treatment and management, and the clinical data were analyzed.Results Among the74 cases of liver transplantation patients which affected by pulmonary fungal infection accounted for14.9%(11/74). Among11 cases of pulmonary fungal infection after liver transplantation patients, eight patients were cured, the cure rate was72.7%. A total of3 patients died, and the mortality rate was 27.3%.Conclusion Patients with pulmonary fungal infection after liver transplantation showed no typical clinical features, which was easy to interfere the clinical diagnosis. For patients with suspected pulmonary fungal infection sputum(and) blood culture should be done as soon as possible to identify species of fungal, and using drugs in accordance with sensitive antimicrobial susceptibility test is the key to the successful treatment of pulmonary fungal infections in patients underwent liver transplantation.

关 键 词：肝移植 肺部真菌感染 治疗 

分 类 号：R519[医药卫生—内科学] R657.3[医药卫生—临床医学]