中药抗感2号解热镇痛作用研究  

The experimental research on antipyretic and analgesic effects of Anti-fever Ⅱ (抗感Ⅱ号)

作　　者：黄鹏[1] 刘玉英[2] 郭志宏[3] 袁丽珍[2] 范书铎[1] 

机构地区：[1]中国医科大学基础医学院生理教研室,沈阳110001 [2]军事医学科学院放射医学研究所,北京100850 [3]沈阳市和平区妇婴医院,沈阳110005

出　　处：《中药药理与临床》2003年第6期36-38,共3页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：目的 :观察抗感 2号的解热镇痛作用。方法 :用干酵母混悬液制备大鼠发热模型 ;用醋酸和热板两种方法致痛观察小鼠痛反应。结果 :抗感 2号对致热大鼠的体温升高有显著的抑制作用 ,对醋酸致痛小鼠扭体反应及热板法致痛均有明显抑制作用。结论 :抗感 2号对发热和疼痛动物模型有明显解热和镇痛作用。Objective: To study the antipyretic and analgesic effects of Anti-fever Ⅱ. Methods: The antipyretic effect was determined with the models of subcutaneous injection of dried yeast suspension .The analgesic effect was determined with mouse writhing method and mouse hot plate method. Results: Anti-fever Ⅱ could significantly inhibited the fever induced by yest, and lessen writhing times of mice and lengthen pain threshold time. Conclusion: Anti-fever 2 possesses antipyretic and analgesic effects.

关 键 词：中药 抗感2号 解热镇痛作用 药理 发热模型 

分 类 号：R285.5[医药卫生—中药学]