吸入液氧对海拔3700m高原人体力竭运动后自由基代谢的影响  

The Effects of Inhaling Liquid-oxygen on Human After Exhaustive Excrcise in Free Radical at 3700 m

作　　者：崔建华[1] 战祥总[1] 张西洲[1] 哈振德[1] 王伟[1] 马勇[1] 邢国祥[1] 张芳[1] 

机构地区：[1]解放军第18医院,新疆叶城844900

出　　处：《临床军医杂志》2003年第6期1-3,共3页Clinical Journal of Medical Officers

基　　金：全军指令性课题 ( 0 1L0 62 )

摘　　要：目的　观察吸入液氧对高原人体力竭运动自由基代谢的影响。方法　对进驻海拔 3 70 0m高原 3个月的 1 0名健康青年在吸入液氧 (吸氧组 ,4L/min)和不吸液氧 (对照组 )的条件下 ,采用功率自行车进行递增负荷运动 ,并在安静时 ,运动后测定血中超氧化物歧化酶 (SOD)、总抗氧化能力 (T ACO)、活性氧 (ROS)和丙二醛 (MDA)含量。结果　与安静时比较 ,对照组和吸氧组T ACO ,ROS,MDA均增高 ,SOD吸氧组增高 ,有非常显著差异 (P <0 0 1 ) ,对照组无统计学差异 (P >0 .0 5 )。运动后吸氧组较对照组SOD ,T ACO增高 ,ROS ,MDA降低 (P <0 0 1 )。结论　液态氧能延长供氧时间 ,并能对高原运动造成的自由基损伤有明显抑制作用 。Objective To observe the effects of inhaling liquid-oxygen on human afler exhaustive exercise in free radical. Methods Applycycle ergometer progressive load exercise to l0 healthy youths after living in 3 700 m plateau for 3 months pre (control group) and post (inhaling group, 4L/min) inhaling liquid oxygen, and assay free radical markers such as SOD.T ACO.ROS and MDA pre-and post exercises. Results The T ACO,ROS and MDA were increased both in the control group and oxygen group after exhaustive exercise, and the SOD increased significantly in oxygen group ( P <0.0l).Compared with control group, the SOD and T ACO were increase but the ROS and MDA were decreased significanly after eahaustive exercise( P <0,01).Conclusion Inhaling liquid oxygen can prolong oxygen supply time,could prevent from fatigue by antagonizing free radicals damage,hastening remove of free radical,which facilitate the recovery from fatigue after exercises.

关 键 词：液氧吸入 高原人体力竭运动 自由基代谢 血氧浓度 

分 类 号：R594.3[医药卫生—内科学] R459.6[医药卫生—临床医学]