废用性骨质疏松症的诊断分型与相关因素探讨  

The diagnosis and classification of disused osteoporosis and its related factors

作　　者：顾敏琪[1] 邓磊[1] 刘沂[2] 黄雷 刘兴华[2] 李谨[3] 

机构地区：[1]中国中医研究院西苑医院骨科,北京100091 [2]北京积水潭医院创伤骨科 [3]北京积水潭医院骨密度研究室

出　　处：《中国骨肿瘤骨病》2003年第6期374-376,共3页Chinse Journal Of Bone Tumor And Bone Disease

摘　　要：目的 研究废用性骨质疏松的诊断分型及其影响因素。方法 采用DEXA测定36例肱骨、股骨和胫骨骨折不愈合患者患肢与健肢3个部位的BMD值,测量部位位于患骨的上下干骺端及骨折远或近端5cm处,并进行统计学的分析比较,确定其诊断分类和讨论相关的影响因素。结果 患侧和健侧测定值,经统计学分析比较,有极显著差异P<0.01,按中国骨质疏松委员会制定的标准,废用性骨质疏松可分为骨量减少和骨质疏松两大类,分别占36.1％和41.7％,总计77.8％。并按年龄、性别、骨折不愈合类型和有无合并感染进行分析比较,结果仅合并感染者可加重骨质疏松,感染与无感染两组病例相比,P<0.05。结论 采用DEXA测定BMD值的方法,按骨量丢失的轻重程度进行诊断分类,可靠性强,临床应用价值大。感染是加重废用性骨质疏松的相关因素。Objective To study the diagnosis and classification of disused osteoporosis and its related factors. Method The Measurements of BMD were made by DEXA in 36 cases with non - union of humeral, femoral and tibial fracture at the sites of both metaphysis of limb and 5 cm area upper or lower fracture end. The results were analyzed sta- tistically, the diagnosis criteria, classification and its influence factors were then discussed. Results Comparing the BMD values in normal and affected bones statistically, there were significant differences between BMD values measured at three sites in each pair respectively, P<0. 01. According to the criteria that were adopted by state osteoporosis commit- tee, the disused osteoporosis can be divided into two types: osteopenia (31.6%) and osteoporosis (41.7%), and sum total is 77. 8 %. The results were compared according to age, gender, the type of nonunion and have or did not have coexisted infection. Only infection aggravated the disused osteoporosis, P<0.05. Conclusion Diagnosing and classi- fying disused osteoporosis according to the quantity of bone mass loss by DEXA is credible and valuable in clinical appli- cation. Infection is a related factor that aggravated disused osteoporosis.

关 键 词：废用性骨质疏松症 诊断 骨折 骨密度 BMD 治疗 

分 类 号：R58[医药卫生—内分泌]