乙型肝炎病毒前S1抗原与HBV血清标志物之间的相关性探讨  

The relativity between Pre-S1 antigen and hepatitis B virus serum markers

作　　者：杨志[1] 陈兰英[1] 周铭[1] 周丽霞[1] 

机构地区：[1]上海市中西医结合医院检验科,200082

出　　处：《蚌埠医学院学报》2004年第1期77-79,共3页Journal of Bengbu Medical College

摘　　要：目的 :探讨乙型肝炎病毒前S1抗原与HBV血清标志物 (即“乙肝五项”)之间的相关性。方法 :用ELISA法检测 4 5 7例HBsAg(+)血清 ,分析其“乙肝五项”与前S1抗原之间的关系。 结果 :前S1抗原与“乙肝五项”有不同的相关性 ,其具有独立的检测价值。结论 :前S1抗原作为HBV感染、复制的指标较HBeAg更敏感 ,与乙型肝炎的活动性有关 ,对“乙肝五项”Objective:To investigate the relativity between Pre S1 antigen and hepatitis B virus serum markers(HBV M).Methods:Four hundred and fifty seven HBsAg positive serums were inspected by ELISA and the relationship between HBV M and Pre S1 antigen were analyzed.Results:Pre S1 antigen and HBV M had different relativity and independent inspection value.Conclusions:As the index of infection and reproduction of HBV,Pre S1 antigen is much more sensitive than HBeAg.Pre S1 antigen is related to the activity of HBV and has the supplemental function to HBV M inspection.

关 键 词：乙型肝炎病毒 前S1抗原 HBV血清标志物 

分 类 号：R373.21[医药卫生—病原生物学]