充血性心力衰竭病人昼夜心脏自主神经功能与平均心率的研究  

Circadian cardiac autonomic nervous activity and average heart rate in patients with congestive Heart failure

作　　者：刘勇[1] 杨涛[1] 

机构地区：[1]四川省自贡市第二人民医院

出　　处：《中西医结合心脑血管病杂志》2004年第1期15-16,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的 :了解充血性心力衰竭病人心脏自主神经活性和平均心率的昼夜改变。方法 :对 5 9例充血性心力衰竭病人 (心力衰竭组 )和 40例健康者 (对照组 )经Holter记录进行 2 4h长程心功率谱分析和平均心率计算。结果 :心力衰竭组清醒期或睡眠期LFnu均明显升高而HFnu明显降低 (P <0 .0 1或P <0 .0 5 ) ,LF/HF均大于对照组 (P <0 .0 5 ) ,同时心力衰竭组夜间平均心率明显高于对照组(P <0 .0 1)。结论 :心力衰竭病人昼夜交感神经活性均升高 ,同时伴迷走神经活性减退 ,这种改变与心力衰竭病人夜间平均心率明显高于对照组可能有内在联系。Objective:To study the Circadian changes of cardiac autonomic nervous activity and average heart rate in patients with CHF. Methods:24-hour heart rate power spectral analysis and heart rate calculating by Holter were performed in 59 patient with CHF and 40 controls. Results:In CHF group, Lfnu and LF/HF increased apparently but HFnu were reverse (P<0.01 or P<0.05) both daytime and nighttime. Nighttime average heart rate in CHF group was higher than control group (P<0.05). Conclusion:In CHF patient ,s, sympathetic activity was increased from daytime to nighttime but parasympathetic activity was decreased, these changes may be correlation to rising of nighttime average heart rate.

关 键 词：充血性心力衰竭 心脏自主神经功能 心率 昼夜改变 

分 类 号：R541.61[医药卫生—心血管疾病]