中越猕猴桃地上部分抗肿瘤作用的实验研究  

Experimental study on antineoplastic effects of the aerial parts of Actinidia indochinensis

作　　者：韦金育[1] 韦涛[1] 李延[1] 吕琳[1] 曾振东[1] 

机构地区：[1]广西民族医药研究所,南宁530001

出　　处：《广西医学》2004年第2期164-166,共3页Guangxi Medical Journal

基　　金：国家自然科学基金资助项目 (30 0 6 0 0 93);广西自然科学基金匹配项目 (0 135 0 2 1)

摘　　要：目的　了解中越猕猴桃地上部分的抗肿瘤作用。方法　用 MTT法及动物移植性肿瘤实验方法研究其抑制肿瘤作用。结果　中越猕猴桃茎、叶、果多种提取物稀释 10 0倍对肝癌细胞仍有明显抑制作用 ,抑制率 31.3%～ 5 4 .5 %。体内抑瘤试验表明 ,茎乙醇、乙酸乙酯、正丁醇提取物对小鼠肝癌 H2 2 的抑制率分别为 30 .3%、33.1%、34.5 % ;叶乙醇提取物对 S1 80 抑制率为31.7% ;茎乙醇、乙酸乙酯、正丁醇提取物对 S1 80 的抑制率分别为 35 .9%、34.8%、32 .2 %。结论　中越猕猴桃果、叶及茎的多种提取物具有抗肿瘤作用。Objective To make a research in antineoplastic effects of the aerial parts of Actinidia indochinensis.Methods The experimental ways of MTT and tumour transplantation in animal were used to study the effect on restraining tumour.Results Many ingredient were extracted from the stem、leaf and fruit of Actinidia indochinensis.All of them that were diluted into 100 times do great effect on tumour,the repression ratio is 31.3%~54.5%.The experiment of restraining tumour in body show that effective ingredients in stem were extracted by alcohol、acid ethylester and n-butanol,the repressive ratio of liver cancer H 22 in rat is 30.3%、33.1% and 34.5% respectively;effective ingredients in leaf were extracted by alcohol,the repressive ratio of S 180 is 31.7%;effective ingredients in stem were extracted by alcohol、acid ethylester and n-butanol,the repressive ratio of S 180 is 35.9%、34.8% and 32.2% respectively.Conclusion Many ingredient which were extracted from the stem、leaf and friut of Actinidia indochinensis had a clearly antitumour action.

关 键 词：中越猕猴桃 地上部分 抗肿瘤作用 实验研究 

分 类 号：R285.5[医药卫生—中药学]