复方丹参注射液对大鼠急性胰腺炎的预防作用  

THE PROPHYLACTIC EFFECTS OF THE COMPOUND INJECTION OF TANSHINONE ON THE EXPERI-MENTAL WHITE RATS WITH ACUTE PANCREATITIS

作　　者：石景森[1] 马庆久[1] 田和平[1] 刘绍诰[1] 孟清翠[1] 韩美蓉 

机构地区：[1]西安医科大学第一附属医院肝胆外科研究室,西安710061

出　　处：《西安医科大学学报》1992年第1期69-71,100,共4页Journal of Xi'an Medical University(Chinese)

摘　　要：本文报道了丹参注射液在大鼠急性胰腺炎模型中对胰腺组织的保护作用,复方丹参注射液能明显减轻实验大鼠胰腺的出血及坏死程度,降低大鼠的死亡率。血清超氧化物歧化酶(SOD)的检测结果:丹参保护组较急性胰腺炎(AP)组SOD的含量明显降低。提示丹参注射液通过改善胰腺的微循环,提高胰腺组织对缺氧的耐受性,减少氧自由基的产生,而最终减轻胰腺的病变程度。In this article the prophylactic effects of the compound injection of tanshinone to panereatic tissues in the experimental white rats with acute pancreatitis was reported. The compound injection of tanshinone could retard the degrec of pancreatic hemorrhage and necrosis of the experimental white rats. It could also reduce the fatality rate of the animal, The value of serum superoxide dismutase in tanshinone protected group were significantly low or than that of nonprotected group The result suggested that the compound injection tanshinone might minimize the pathological change degrees of the panereatie tissue by means of improving microcirculation of the pancreatic tissues, enhencing the tolerence of the pancrease to anoxia, reducing generation of the free redical.

关 键 词：急性 胰腺炎 丹参注射液 

分 类 号：R657.51[医药卫生—外科学]