淫羊藿总黄酮对家兔血液流变学指标的影响  

EFFECTS OF FLAVONES OF EPINEDIUM BREVICORNUM MAXIM ON HEMORRHEOLOGICAL PARAMETERS OF RABBITS

作　　者：高其铭[1] 袁秉祥[1] 赵苏玉 李生正[3] 刘次伯[3] 

机构地区：[1]西安医科大学药学系药理教研室,西安710061 [2]西安老年病医 [3]西安医科大学药学系有机化学教研室

出　　处：《西安医科大学学报》1992年第3期223-226,共4页Journal of Xi'an Medical University(Chinese)

摘　　要：研究淫羊藿总黄酮(FEBM)对家兔血液流变学指标的影响,结果表明:FEBM在0.1g/kg或0.4g/kg时,每天两次灌胃,连续3d,可抑制家兔体外血栓形成;在0.4g/kg时可降低2～40s^(-1)切变率时的全血粘度和抑制红细胞的聚集。实验说明FEBM抑制血栓形成的主要因素可能和降低红细胞聚集性及降低全血粘度有关。The effects of flavones of epinedium brevicornum maxim (FEBM) on hemorrheological Parameters of rabbits were studied. It was found that FEBM at 0.1 or 0.4g·kg^(-1)·d^(-1)ig b. i. d. could inhibit thrombosis in vitro,at 0.4 g·kg^(-1)· d^(-1) could reduce blood mucosity at 2～40 s^(-1) shearing and inhibit agglutination of red cells. It was demonstrated that the inhibition of thrombosis and the reduction of blood mucosity might be due to the effects of FEBM on agglutination of red cells.

关 键 词：淫羊藿总黄酮 血液流变学 

分 类 号：R282.710.5[医药卫生—中药学]