复苏饮对重症脑出血患者炎症细胞因子的影响  

Effict of Fusu Decoction on Inflammation Cytokine of Patients with Severe Cerebral Hemorrhage

作　　者：罗小星[1] 赵永华[1] 赵锋利[1] 

机构地区：[1]广州中医药大学第一附属医院,广州510405

出　　处：《中国中医急症》2004年第2期70-71,共2页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察复苏饮对重症脑出血患者炎症细胞因子的影响。方法将126例重症脑出血患者随机分为两组,对照组予西医综合疗法,中药组在此基础上加用复苏饮,分别于用药前及用药后48h抽取患者静脉血检测肿瘤坏死因子-α(TNF-α)、白细胞介素-1(IL-1)、白细胞介素-6(IL-6),比较用药前后炎症细胞因子的变化。结果两组TNF-α、IL-1、IL-6在治疗后均有不同程度的下降,但以中药组下降更明显。结论复苏饮可以降低重症脑出血患者炎症细胞因子,此点可为治疗提供一定的药理学依据。Objective:To observe the effect of Fusu Decoction on inflammation cytokine of pa tients with severe cerebral hemorrhage.Methods:126 patients with severe cerebral hemorrhage were divided randomly into two groups,the TCM group and the controll ed group.Patients in the controlled group were given composite therapy of WM,whe reas those in the TCM group were extra added with Fusu Decoction on the base of routine therapy. The levels of TNF-á,IL-1 and IL-6 were measured before and after treatment.Results:The levels of TNF-á,IL-1 and IL-6 of patients in bot h groups decreased by degrees,while the condition in the TCM group was superior to that in the controlled group. Conclusion:Fusu Decoction could reduce inflamma tion cytokine of patients with severe cerebral hemorrhage,and provide some pharm acology evidence according the result.

关 键 词：复苏饮 重症脑出血 炎症细胞因子 肿瘤坏死因子-α 检测 白细胞介素-1 白细胞介素-6 

分 类 号：R277.733.4[医药卫生—中医学]