鸡生长轴相关基因的研究进展  

Progress of the Research on Chicken Growth Axis-related Genes

作　　者：聂庆华[1] 张细权[1] 杨关福[1] 

机构地区：[1]华南农业大学动物科学学院,广州510642

出　　处：《农业生物技术学报》2003年第3期305-312,共8页Journal of Agricultural Biotechnology

基　　金：国家重大基础研究规划项目(G2000016102)。

摘　　要：神经内分泌生长轴,又称脑垂体生长轴,在动物的生长发育过程中发挥重要的调节作用。下丘脑分泌的生长抑素(somatostatin,SS)和生长激素释放激素(growthhormonereleasinghormone,GHRH)、垂体分泌的鸡生长激素(chickengrowthhormone,cGH)、靶器官(如肝脏)分泌的鸡生长激素受体(chickengrowthhormonereceptor,cGHR)和胰岛素样生长因子-Ⅰ(insulin-likegrowthfactor-Ⅰ,IGF-Ⅰ),以及下丘脑-垂体-靶器官作用通路构成了鸡生长轴的基本内容。介绍了近几年来鸡生长轴的各激素(因子)及其受体的基因研究,以及相互间的作用机制,以进一步探索家禽的生长调控机理。Neurocrine axis or hypothalamus-pituitary growth axis plays a major role of regulation in the progress of animal growth and development. It consists of somatostatin(SS) and growth hormone releasing hormone(GHRH) secreted by hypothalamus, growth hormone secreted by pituitary, chicken growth hormone receptor and insulin-like growth factor-Ⅰsecreted by target organs(such as liver), as well as the path of hypothalamus-pituitary-target organs. Analysis of related genes in chicken growth axis and their interaction mechanism were reviewed in order to understand more about the regulation mechanism of poultry growth.

关 键 词：鸡 生长轴 鸡生长激素 鸡生长激素受体 胰岛素样生长因子 

分 类 号：S831[农业科学—畜牧学]