静脉注射丙种球蛋白在新生儿重症高未结合胆红素血症的疗效分析  

Analysis of the effect of intravenious gamma globin in the treatment of newborn severe bilirubinemia

作　　者：周新玲[1] 彭东兰[1] 万钧[1] 

机构地区：[1]吉安市中心人民医院,江西吉安343000

出　　处：《井冈山医专学报》2004年第1期5-6,共2页Journal of Jinggangshan Medical College

摘　　要：目的探讨新生儿高未结合胆红素血症的更好内科治疗方法。方法对12例新生儿重症高未结合胆红素血症患儿在常规治疗的基础上,加用静脉注射丙种球蛋白(IVIG)1g/kg/d,6～8h输完,连用1～3d,并在治疗前1d、治疗后每1天连续监测血清胆红素浓度。结果IVIG联合光疗等常规方法,能更快地下降血清胆红素浓度,缩短黄疸消退时间,减少光疗时间,具有显著性意义。结论IVIG治疗新生儿高未结合胆红素血症有确切疗效。基层医院因条件受限,对重症新生儿高未结合胆红素血症,不能实施换血治疗,可加用IVIG以达到部分换血的目的。Objective:To investigate the well medical therapy of newborn severe bilirubinemia.Methods:12 patients of newborn severe bilirubinemia received the intravenous gamma globin(1 g/kg/d,for 6 to 8 hours)besides the routine treatment,A treatment period of 1 to 3 days,and the concentration of blood serum bilirubin of the patient was detected one day before and after treatment.Results:After the treatment of intravenous gamma globin and ray therapy,the concentration of blood serum bilirubin decreased and it was marked to shorten the time of fadeaway of icterus and ray therapy.Conclusion:The effect of intravenous gamma globin in the treatment of newborn severe bilirubinemia was accurate,but the patients of newborn severe bilirubinemia were not exchanged the blood for the limit of the condition of basal hospital,the patients with intravenous gamma globin were exchanged the part of the blood.

关 键 词：静脉注射丙种球蛋白 新生儿重症高未结合胆红素血症 

分 类 号：R725.5[医药卫生—儿科]