我国青年人群血清中流感抗体的连续三年监测  

Survey research of serum anti-influenza virus antibody levels in Chinese young people during 1997-2000

作　　者：段佩若[1] 赵华[1] 林京[1] 杜豫[1] 

机构地区：[1]第二炮兵总医院中心实验室,北京100088

出　　处：《细胞与分子免疫学杂志》2003年第4期364-365,368,共3页Chinese Journal of Cellular and Molecular Immunology

基　　金：全军医药卫生基金资助课题 (No .0 1MA0 66)

摘　　要：目的 :了解青年人群血清中抗流感病毒的抗体水平和病毒变异程度。方法 :应用微量血凝素抑制试验 ,对从 1997～ 2 0 0 0年在我国 8个地区 ,每年春、秋两季 ,共采集 30 0 0份血清标本进行抗流感病毒抗体水平的检测。结果 :发现人群中抗流感病毒抗体的水平 ,在春、秋两季间波动 ;抗甲 3型流感病毒(H3N2 )的抗体水平 ,从 1999～ 2 0 0 0年保持了高水平 ;而抗甲 1型流感病毒 (H1N1)的抗体水平 ,从 1998年以来呈梯形下降 ,易感人群由 15 %上升到 75 %。结论 :近 3年中流感病毒甲 3型、甲 1型和乙型均曾在我国局部流行 ,甲 1型流感病毒 (H1N1)发生了明显变异 ,甲 3型流感病毒 (H3N2 )AIM: To survery the levels of serum anti influenza virus antibodies and variable extent of the virus in the young people. METHODS: The levels of anti influenza virus antibody in the serum samples collected from 3 000 young people of eight different areas in China in spring and autumn per year during 1997 2000 were detected by microhemagglutination inhibition test. RESULTS: The antibody levels of the young people fluctuated between the spring and autumn per year. The levels of antibody against type A3 virus (H3N2) preserved high from 1999 2000, while the level of antibody to type A1 (H1N1) decreased from 1998 to 2000 and the percentages of people susceptible to this type rose from 15% to 75%. CONCLUSION: The epidemic of H3N2, H1N1 viruses and influenza virus type has occurred at some areas in China. Significant variation appeared in H1N1 virus, while the variation of H3N2 virus will be expected.

关 键 词：流感病毒 抗体水平 青年人群 

分 类 号：R511.7[医药卫生—内科学]