高血压病左心室构型对左心房功能影响的研究  

Evaluation on effect of left ventricular geometric patterns to left atrial function in hypertensive patients using acoustic quantification

作　　者：张薇[1] 崔琪琼[1] 张运[1] 刘丹[1] 黎莉[1] 钟明[1] 葛志明[1] 

机构地区：[1]山东大学齐鲁医院心内科,济南250012

出　　处：《中华超声影像学杂志》2003年第6期333-336,共4页Chinese Journal of Ultrasonography

摘　　要：目的　应用声学定量 (AQ)技术评价高血压病不同左心室构型表达对左心房功能的影响。方法　对照组 2 0例 ,高血压病组 68例 ,根据左心室心肌质量指数 (massindex)和相对室壁厚度 ,将高血压病组分为左心室几何构型正常组、左心室向心性重构组、左心室向心性肥厚组和左心室离心性肥厚组。应用AQ技术 ,测量左心房存储容积 (RV )、射血分数 (LVEF)和管道容积 (CV) ,分别代表左心房存储器功能、助力泵功能和管道功能。结果　与对照组比较 ,几何构型正常组和左心室向心性重构组RV增大 ;向心性肥厚组RV、LAEF增大 ,CV减低 ;离心性肥厚组RV增大 ,LAEF和CV减低。结论　左心房通过其存储器功能、助力泵功能和管道功能的重新分配 ,代偿高血压病不同左心室构型引起的左心室充盈异常 ;左心室离心性肥厚时 ,左心房功能失代偿。Objective To investigate the effect of left ventricular geometric patterns on left atrial performance in patients with hypertension by acoustic quantification (AQ) technique. Methods Sixty eight hypertensive patients and 20 control subjects were studied. According to left ventricular mass index (LVMI) and relative wall thickness, normal left ventricular geometry, concentric remolding, concentric hypertrophy and eccentric hypertrophy were grouped in patients with hypertension. Left atrial ejection fraction (LAEF), conduit volume (CV) and reservoir volume (RV) were measured with AQ technique. Results Compared with control subjects, RV was increased more significantly in patients with normal left ventricular geometry and concentric remolding; RV and LAEF were increased, and CV was decreased significantly in patients with concentric hypertrophy; LAEF and CV were decreased, and RV was increased significantly in patients with eccentric hypertrophy. Conclusions The redistribution of left atrial reservoir function, booster pump function and conduit function is an important compensatory mechanism that facilitates left ventricular filling in hypertensive patients with different left ventricular geometric patterns. Left atrial dysfunction occurs in patients with eccentric hypertrophy.

关 键 词：高血压病 左心室构型 左心房功能 声学定量 左心室肥厚 

分 类 号：R726.8[医药卫生—儿科]