交联琼脂包嵌凹凸棒微囊重复血液灌流中白细胞吞噬功能的变化  

Change of Leukocytic Phagocytosis During Repeat Hemoperfusion with Cross-linked Agar Beads Entrapped Attapulgite Clay

作　　者：黄维[1] 马育[1] 杨晓兰[1] 汤先觉[1] 舒昌达[1] 

机构地区：[1]重庆医科大学,重庆400016

出　　处：《生物医学工程学杂志》2003年第2期302-304,共3页Journal of Biomedical Engineering

基　　金：重庆市医学科技计划资助项目 (99-2 0 3 2 )

摘　　要：研究了交联琼脂包嵌凹凸棒微囊 (CAA)在正常大白鼠血液灌流中的白细胞的吞噬率及吞噬指数。发现灌流 1h后其值明显下降 ,6 h后逐渐上升 ,至到 4 8h已基本恢复正常。重复血液灌流两次 ,结果类似 ,说明交联琼脂包嵌凹凸棒微囊血液灌流对机体白细胞吞噬功能的降低是暂时的 。The leukocytic phagocytosis rate and the index of phagocytosis of rats on cross linked agar beads entrapped attapulgite clay (CAA) hemoperfusion were studied. The results revealed that the leukocytic phagocytosis rate and the index of phagocytosis descended significantly after 1 hour and rose gradually after 6 hours. Finally it reached the normal level after 48 hours. Hemoperfusion repeated two times gave similar results.In conclusion, the function of leukocytic phagocytosis declined temporarily during CAA hemoperfusion. Many times hemoperfusion will not notablely affect the body's defense system of rats.

关 键 词：交联琼脂包嵌凹凸棒微囊 血液灌流 白细胞 吞噬功能 吸附材料 血液相容性 

分 类 号：R318.08[医药卫生—生物医学工程]