荧光定量PCR检测HBV-DNA  

Nucleic acid Puantifying Assay of Hepatitis b virus and its Clinical significance

作　　者：周建华[1] 万小涛[1] 蒋维国[1] 廖常贵[1] 

机构地区：[1]内江市第一人民医院,四川内江641000

出　　处：《川北医学院学报》2003年第4期106-107,共2页Journal of North Sichuan Medical College

摘　　要：目的 探讨血清HBV-DNA水平与HBV标志物(HBVM)表现模式的关系。方法对1223例慢性乙型肝炎患者进行血HBV-DNA荧光定量PCR分析,HBVM检测采用ELISA法。结果血清HBV-DNA水平与HBV M表现模式有关,HbsAg与HbeAg的存在影响HBV-DNA水平变化。结论HbeAg水平与HBV-DNA有明显的相关,抗-Hbc、抗HBc阳性者病毒未完全停止复制,只是复制水平降低。Objective To explore the relation between the nucleic acid content of hepatitis B Virus and hepatitis Bvirus markers. Methods: 1207 patients Suffering from Chronic hepatitis B were detected by ELISA Results: Serum HBV HDA content was related to hepatitis B virus markers. Conclusions:There is a Significant correlation between HbeAg and HBV - DNA, but positive Anti - Hbe and Anti - HBc have copies lower coyer.

关 键 词：荧光定量 PCR 检测 HBV-DNA 血清 乙型肝炎 

分 类 号：R512.62[医药卫生—内科学] R446.62[医药卫生—临床医学]