生活事件应激对心血管病危险因素影响的纵向数据分析  

Longitudinal data analysis of the effect of provoking life events on cardiovascular risk factors

作　　者：李彦兵[1] 贾立辉[1] 陈琨[1] 

机构地区：[1]解放军沈阳军区总医院医务部,辽宁省沈阳市110016

出　　处：《中国临床康复》2004年第3期401-403,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:观察生活事件应激对心血管病危险因素的影响,论证心理干预的重要性。方法:198例常年在解放军沈阳军区总医院体检的健康中老年人,在2002年体检中,测评了在2000/2001遭遇的生活事件,计算出生活事件应激单位(lifeeventsunit,LEU),并分为高LEU组(LEU≥43.6/年,73例)和低LEU组((LEU<43.6/年,125例),从每年的体检资料中收集到两组对象的血压,总胆固醇、三酰甘油和高密度脂蛋白胆固醇(HDL-C)、血糖、腹围和体重指数等数据进行比较,在2002年体检中还增加了精神心理状态量表(SCL-90)评估。结果:2000年数据中两组对象的年龄、血压、血脂、血糖、腹围和体质量指数等分布接近(P均>0.05)。2002年数据中高LEU组的平均收缩压(133.6±38.2)mmHg、舒张压(83.9±27.5)mmHg和总胆固醇(4.9±1.6)mmol/L明显高于低LEU组(t=1.995～2.965;P均<0.01～0.05)。高LEU组2000和2002年数据自身比较中,前者中的平均收缩压(129.7±32.3)mmHg、舒张压(80.6±22.8)mmHg、血糖(5.8±1.9)mmol/L和总胆固醇(4.7±1.2)mmol/L均明显低于后者(t=1.979～2.551,P均<0.05)。两组对象的SCL-90评估中,高LEU组的人际关系(1.86±0.39)、抑郁(1.87±0.45)、焦虑(1.61±0.31),偏执(1.25±0.29)和精神病性(1.48±0.36)均明显高于低LEU组(t=2.446～2.AIM:To explore the effect of provoking life events(LE) on cardiovascular risk factors and to explain the importance of psychological intervention. METHODS:198 healthy subjects,aged or middle- aged,performed physical examina tion every year in the General Hospital of Shenyang Military Region.The scale of LE unit(LEU) in all subjects were measured during the physical examination of 2 002,they were divided into two groups according to the scale of LEU high or low. The high scale group(HSG) had 73 cases(LEU≥ 43.6/year) and the low scale group( LSG) had 125 cases(LEU< 43.6/year).The values of blood pressure(BP),total choles terol(TC),triacylglycerol(TG),high- density lipoproteir cholesterol(HDL- C),pl asma glucose(PG),waist circumference(WC) and body mass index(BMI) in both groups were collected from data every year,and were compared.The values of SCL- 90 we re measured in the two groups during physical examination of 2002. RESULTS:The values of age,BP,blood lipid,PG,WC and BMI in both groups were ve ry close in 2002(P >0.05).The mean systolic blood pressure(SBP)[(133.6± 38.2) m mHg],mean diastolic blood pressure(DBP)[(83.9± 27.5) mmHg] and TC[( 4.9± 1.6 ) mmol/L] in the HSG were obviously higher than those in the LSG in 2002(t=1.9 95-2.965,P< 0.01-0.05).The values of SBP[( 129.7± 32.3) mmHg],[DBP( 80. 6± 22.8) mmHg],PG[( 5.8± 1.9) mmol/L],TC[( 4.7± 1.2) mmol/L] of 2000 in the HSG were significantly lower than those of 2002(t=1.979-2.551,P< 0.05). The average scales of human relation(1.86± 0.39), depression(1.87± 0.45),anxie ty(1.61± 0.31),paranoiac(1.25± 0.29)and psychosis (1.48± 0.36) in the HSG wer e obviously higher than those in the LSG in 2002(t=2.446-2.954, P< 0.05).Provoking life events can affect the values of SBP,DBP,PG,TC of a ged and middle- aged people greatly.

关 键 词：生活事件 应激反应 心血管病 危险因素 数据 心理反应 血糖 

分 类 号：R54[医药卫生—心血管疾病]