连翘提取物的体外抗菌试验  

Antibacterial effect in vitro of extracts from fructus forsythiae

作　　者：白云娥[1] 漆小梅[1] 杨国红[1] 李青山[1] 王明杰 

机构地区：[1]山西医科大学药学院中药室,太原030001 [2]运城市盐化局职工医院

出　　处：《山西医科大学学报》2003年第6期506-507,共2页Journal of Shanxi Medical University

摘　　要：目的　筛选连翘制剂工艺。方法　液体两倍稀释法分别测定提取物的最低抑菌浓度 (MIC)和最低杀菌浓度 (MBC)。结果　连翘提取物对金黄色葡萄球菌、肺炎链球菌较敏感 ;对大肠杆菌不太敏感 ;对白色念珠菌不敏感。样品 4和样品 5的工艺较优。结论　体外抗菌试验为筛选抗菌药物的有效途径之一。Objective To screen the preparation procedure for fructus forsythiae. Method The method of doubling delution in test tube was used to detect the MIC and MBC of extracts to bacteria. Results The extracts had a good bacteriostaic effect to Staphylococcus aureus and Treptococcus pneumoniae , but did not exhibit Candida albicans activity.The effect was not very good to Eschericha coli .The preparetion procedures for samples 4 and 5 was optimum. Conclusion Antibacterial effect test in vitro is one of effective ways for screening optimal antibacterial drugs. This test provide a reliable reference for preparative procedure of fructus forsythiae.

关 键 词：连翘 提取物 体外抗菌试验 中草药 

分 类 号：R284.2[医药卫生—中药学]