亚甲基四氢叶酸还原酶(MTHFR)C677T基因多态性与血压变化的相关性研究  

Relevant research on methylenetetrahydrofolate reductase(MTHFR) C677T gen polymorphism and blood pressure change

作　　者：侯志峰[1] 

机构地区：[1]济南军区青岛第一疗养院,266071

出　　处：《中国疗养医学》2016年第8期804-806,共3页Chinese Journal of Convalescent Medicine

摘　　要：高血压和高同型半胱氨酸血症是冠状动脉粥样硬化性心脏病(简称冠心病CVD)的独立危险因素。同型半胱氨酸浓度主要受亚甲基四氢叶酸还原酶(MTHFR)C677T基因多态性的影响,尤其受纯合子(即TT基因型)的影响。本综述旨在研究MTHFR C677T基因多态性与血压变化的关系。High blood pressure and hyperhomocysteinemia(HHcy) are independent risk factors for coronary atherosclerotic heart disease(CVD).Homocysteine concentration is mostly affected by methylenetetrahydrofolate reductase(MTHFR) C677T gene polymorphism,especially by homozygote(TTgenotype).The paper aims to study the relationship between MTHFR C677T gene polymorphism and blood pressure change.

关 键 词：亚甲基四氢叶酸还原酶 C677T基因多态性 同型半胱氨酸 

分 类 号：R544.1[医药卫生—心血管疾病] R541.4[医药卫生—内科学]