兔病毒性出血症、多杀性巴氏杆菌病二联蜂胶灭活疫苗与相应单苗免疫效力的比较试验  被引量:1

Comparison of Immunuity of Bicombinant Propolis-adjuvant Inactivated Vaccine Against Rabbit Hemorrhagic Disaese and Pasteurellosis with the Two Corresponding Single Vaccine

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作  者:王晓丽 王永明 孟薇薇 赵飞飞 李士成 

机构地区:[1]山东华宏生物工程有限公司,滨州256600

出  处:《中国养兔》2015年第3期10-13,共4页Chinese Journal of Rabbit Farming

摘  要:兔病毒性出血症、多杀性巴氏杆菌病二联蜂胶灭活疫苗分别与两种单苗进行免疫效力、免疫持续期及保存期的试验,试验结果表明:二联蜂胶灭活疫苗对兔病毒性出血症的免疫保护率为100%(10/10),对多杀性巴氏杆菌病的免疫保护率为90%(9/10),而两种单苗的免疫保护均为100%(10/10);二联苗和单苗免疫后第3天对兔病毒性出血症产生部分免疫力,至第10天产生坚强免疫力而对多杀性巴氏杆菌第14天产生坚强免疫力;二联苗和单苗免疫6个月后,对兔病毒性出血症的免疫保护为100%(10/10),对多杀性巴氏杆菌病的免疫保护为90%(9/10);二联苗和单苗在2~8℃和室温条件下保存15个月后,对兔病毒性出血症的免疫保护为100%(10/10),对多杀性巴氏杆菌病的免疫保护为90%(9/10)。二联苗中两组分的配比科学合理且两者之间无干扰作用。Immunity of bicombinant propolis-adjuvant inactivated vaccine against RHD and Pm was compared with the two corresponding single vaccines.The results showed that the protection rates of rabbits immunized with the bicombinant proplis-adjuvant inactivated vaccine were 100%(10/10) and 90%(9/10), and those of the single RHD vaccine and the Pm vaccine were 100%(10/10) and 90%(9/10). The immune protection rate of the combined vaccine and the single vaccine against RHD was producted on 3th day vaccination, immunity induce was more strong on 10th day, and those against Pm was producted later than RHD, immunity induce was more strong on 14th day. After vaccination 6 months,the efficacies of both the combined vaccine and the single vac?cine for RHD was 100%(10/10) and for Pm was 90%(9/10). The combined vaccine and the single vaccine were storaged in 2~8℃and at room temperature for 15 months, protection rate were 100%(10/10) against RHD and 90%(9/10) against Pm. The interfere between RHD and Pm in the combined vaccine did not happen.

关 键 词:疫苗 效力 攻毒 

分 类 号:S858.291[农业科学—临床兽医学]

 

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