慢性阻塞性肺疾病患者有创-无创序贯撤机过程中循环与呼吸功能变化的研究  

Changes in Respiratory and Circulary Function of Patientswith Chronic Obstructive Pulmonary Disease During SequentialInvasive-Noninvasive Mechanical Ventilation

作　　者：戴幼竹[1] 严正[1] 王烨[1] 陆荣国[1] 衡军峰[1] 胡纪根[1] 

机构地区：[1]南京医科大学附属无锡一院ICU,江苏无锡214002

出　　处：《江南大学学报（自然科学版）》2003年第5期542-544,共3页Joural of Jiangnan University (Natural Science Edition)　

摘　　要：目的　了解有创-无创机械通气治疗慢性阻塞性肺疾病(COPD)患者呼吸和循环功能的变化,评价该法的生理效应 方法　选择接受机械通气的COPD合并呼衰患者13例,待符合拔管条件后,拔除气管插管,改用经面罩压力支持通气+呼气末正压通气(PSV+PEEP) 分别于基本符合拔管条件下的机械通气时,以及拔管后3h条件下测定患者的呼吸和循环功能的变化 结果有创通气向无创通气转换过程中,循环呼吸参数的变化无显著差异性(p>0 05) 结论　有创-无创机械通气撤机过程中,患者的呼吸和循环功能稳定。OBJECTIVE To investigate the change of respiratory and circulatory function of patients with COPD during sequential invasive noninvasive mechanial ventilation. METHOD 13 COPD patients with respiratory failure were ventilated by endotracheal intubation. When the case was in accord with the condition of extubation, they were extubated and received mask ventilation. The parameters of blood gas and hemodynamics were measured during endotracheal ventilation and mask ventilation (3 hrs after extubation)respectively. RESULT The changes of respiratory and circulatory parameters were of no signifcant difference between invasive mechanial ventilation and noinvasive mechanical vetilation (P>0.05). CONCLUSION The respiratory and circulatory function of COPD patients remained stable during sequential invasive-noninvasive mechanical ventilation.

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 机械通气 

分 类 号：R563.1[医药卫生—呼吸系统]