子宫血流测定在体外受精新鲜移植周期中的应用  

Application of invitro fertilization fresh transfer cycles in the uterine blood flow measurement

作　　者：张昀[1] 项静英[1] 陈洁[1] 徐洪燕[1] 熊芳[1] 周萍[1] 

机构地区：[1]南京医科大学附属无锡妇幼保健院生殖医学科,江苏无锡214002

出　　处：《江苏大学学报（医学版）》2015年第5期431-434,共4页Journal of Jiangsu University：Medicine Edition

摘　　要：目的:探讨体外受精-胚胎移植(invitro fertilization and embryo transfer,IVF-ET)中子宫动脉血流和子宫内膜(下)血流分布与妊娠结局的相关性。方法:选取61例不孕症患者进行IVF-ET,采用阴道彩色多普勒超声成像技术检测人绒毛膜促性腺激素(human chorionic gonadotropin,HCG)注射日和胚胎移植日的子宫动脉血流阻力指数、搏动指数及内膜(下)的血流灌注情况,根据妊娠结果分为妊娠组和非妊娠组,比较两组间各参数的差异。根据内膜(下)的血流灌注类型将患者分为A型、B型、C型3组,比较各组间妊娠结果差异。结果:妊娠组与非妊娠组HCG注射日、胚胎移植日子宫动脉血流阻力指数、搏动指数相比,差异均无统计学意义(P均>0.05)。HCG注射日A型、B型、C型3组妊娠率差异无统计学意义(χ2=0.02,P>0.05),而胚胎移植日3组妊娠率差异有统计学意义(χ2=6.16,P<0.05)。结论:IVF-ET过程中检测胚胎移植日子宫动脉血流及内膜(下)的血流灌注情况,对妊娠结局有一定的预测价值。Objective:To investigate the relationship between the uterine artery blood flow and endome-trial blood flow measured and the outcome of pregnancy in invitro fertilization and embryo transfer(IVF-ET) fresh transfer cycles.Methods:A total of 61 women undergoing IVF-ET were included in the study.Trans-vaginal color doppler sonography (TV-CDS)was used to monitor the blood flow of uterine artery resistance index(RI),pulsation index(PI)and endometrial(sub endometrial )blood flow which include the day of human chorionic gonadotropin(HCG)injection and the day of embryos transfer during IVF-ET cycles.Ac-cording to the outcome of pregnancy,patients were divided into pregnancy group and non-pregnancy group, compared the parameters between the two groups.According to the situation of the endometrial (sub endom-etrial )blood flow,patients were divided into three groups:type A,type B and type C group,compared the parameters in the three groups.Results:There was no difference in the uterine artery blood status between the pregnancy group and non-pregnancy group (P >0.05).There was also no difference in the rate of preg-nancy during the day of HCG injection between type A,B and C group (χ2 =0.02,P >0.05).While there was significant difference in the rate of pregnancy during the day of embryos transfered between type A,B and C group (χ2 =6.16,P <0.05).Conclusion:Endometrial perforating blood flow in the day of embryos trans-fered could be used as a factor for forecasting the outcomes of IVF-ET.

关 键 词：体外受精-胚胎移植 经阴道彩色多普勒 子宫内膜血流 

分 类 号：R714.8[医药卫生—妇产科学]