巨噬细胞在损伤时间推断中的作用  

The role of macrophages in wound age estimation during the wound healing process

作　　者：李学锋[1] 王慧君[1] 

机构地区：[1]第一军医大学病理学教研室法医组,广东广州510515

出　　处：《法医学杂志》2003年第2期122-125,共4页Journal of Forensic Medicine

摘　　要：综述了近年来巨噬细胞在损伤时间推断中的法医学作用的研究进展。论述了巨噬细胞源性细胞因子的表达、巨噬细胞表型的变化和巨噬细胞吞噬物的演化等变化与损伤时间的关系,认为巨噬细胞在损伤修复中的特征性变化可作为损伤时间推断的新指标,具有深入研究的必要。The article reviewed the advance and the forensic meaning of macrophage on the wound age estimation during the wound healing process in resent years. It has also been summarized the relationship between macrophages and wound age estimation on the expression of cytokines derived from macrophages,the changes of macrophage phenotypes and the development process of phagosomes in macrophages after wounding. It is suggested that some regular and characteristic changes of macrophage should be a useful mark to wound age estimation and reminds therefore further study in this field.

关 键 词：巨噬细胞 损伤时间 法医学 细胞因子 创伤修复 

分 类 号：R641[医药卫生—外科学] D919.4[医药卫生—临床医学]