伴行血管在高强度聚焦超声下对温度场的影响  

Effect of Unequal Countercurrent Blood Vessels on the Temperature Distribution Due to HIFU

作　　者：陈琦[1] 白景峰[1] 陈亚珠[1] 

机构地区：[1]上海交通大学生物医学仪器研究所,上海200030

出　　处：《上海交通大学学报》2004年第1期130-134,共5页Journal of Shanghai Jiaotong University

摘　　要：在高强度聚焦超声(HIFU)下,研究了管径不同的伴行血管对于组织温度分布的影响.基于3个热平衡方程提出了1个生物热传导模型,针对带有直径为50～300μm成对血管的组织,利用有限元方法进行了3-D温度瞬态仿真,并对血管直径、血液流速和血液灌流率对3-D温度分布的影响进行了比较.结果表明,血管直径和血流速度是影响HIFU作用下组织温度分布的决定因素,此外,该模型可以给出较为准确的组织消融量.The paper investigated the effect of unequal countercurrent blood vessels on the temperature distribution during phased high intensity focused ultrasound (HIFU) treatment. A bioheat transfer model based on three heat balance equations was adapted for 3-D transient simulations. The simulation of this model using finite element method was carried out for the tissue with the 50-300 μm diameter paired blood vessels. Contribution from the vessel diameter, blood velocity and blood perfusion rate were compared and the influence on 3-D temperature distribution was estimated. The results show that the paired vessel diameter and the blood velocity are the crucial factors determining the distribution of temperature for HIFU treatment. Moreover, the model is able to give more precise information about the lesion volume of heated tissue.

关 键 词：生物热传导 高强度聚焦超声 形状因子 有限元法 

分 类 号：O551[理学—热学与物质分子运动论]