心脉通胶囊对急性心肌梗塞患者顿抑心肌的保护作用及机制探讨  

Protective Effect of Xinmaitong Capsules on Stunned Myocardium in the Patients with Acute Myocardiac Infarction:Investigation of the Mechanism

作　　者：孟君[1] 冯君[1] 丘瑞香[1] 蓝军 贺敬波 

机构地区：[1]广东中山医科大学附属第一医院中医科,广东510080 [2]广东东莞石龙人民医院心内科,广东523321 [3]广东深圳宝安区人民医院中医科,广东518000

出　　处：《北京中医药大学学报》2004年第1期66-69,共4页Journal of Beijing University of Traditional Chinese Medicine

摘　　要：目的　探讨中药复方心脉通胶囊对急性心肌梗塞 (AMI)患者顿抑心肌的保护作用及作用机制。方法　 4 6例急性心肌梗塞患者随机分为心脉通胶囊组 (2 3例 ,常规西药加心脉通胶囊治疗 )与对照组 (2 3例 ,单用常规西药治疗 ) ,观察治疗前后AMI患者心脏收缩功能、室壁运动异常指数。结果　心脉通组患者的左室运动功能改善及室壁运动异常指数下降与对照组相比有显著性差异(P <0 0 5 )。结论　心脉通胶囊对改善顿抑心肌的收缩运动和整体功能产生了积极影响 。Objective To investigate the protective effect of Xinmaitong Capsules (XC) on stunned myocardium and the mechanism of the effect in the patients with acute myocardiac infarction (AMI). Methods 46 cases of AMI were randomly divided into the XC group (23 cases, treated with regular western-style medicine and XC) and control group (23 cases, treated with regular western-style medicine only). The systolic function and the dyskinetic index of the ventricular wall were observed in the AMI patients before and after the treatment.Results There was a significant difference between the improvement of the motor function of the left ventricle and the decrease of the dyskinetic index of the ventricular wall in the XC group and those in the control group ( P <0 05).Conclusion XC possess marked effect on the restoration of the motor function of stunned myocardium in the AMI patients.

关 键 词：心脉通胶囊 急性心肌梗塞 顿抑心肌 

分 类 号：R256.22[医药卫生—中医内科学]