Rectal ulcer:Due to ketoprofen, argon plasma coagulation and prostatic brachytherapy  

作　　者：Thibaud Koessler Vincent Servois Pascale Mariani Emilie Aubert Wulfran Cacheux 

机构地区：[1]Department of Oncology, H?pitaux universitaires de Genève [2]Department of Radiology, Institut Curie,75248 Paris, France [3]epartment of Surgical Oncology, Institut Curie, 75248 Paris, France [4]Department of Surgical Oncology, Institut Curie, 75248 Paris, France

出　　处：《World Journal of Gastroenterology》2014年第45期17244-17246,共3页世界胃肠病学杂志（英文版）

基　　金：Supported by Institut Curie,France

摘　　要：Prostatic brachytherapy with permanent seed implants is a recent and safe radiation therapy technique associated with radiation-induced digestive disease.Argon plasma coagulation procedure is a validated modality in the management of haemorrhagic radiation proctitis,which is known to occasionally induce chronic rectal ulcers.We report here an original case report of an acute painful rectal ulcer as a consequence of the combination of shortterm therapy with non-steroidal anti-inflammatory drugs therapy,prostatic brachytherapy with malposition of seed implants and argon plasma coagulation procedure in a patient with haemorrhagic radiation proctitis.The description of this clinical observation is essential to recommend the discontinuation of non-steroidal anti-inflammatory drugs therapy and the control of the position of seed implants in case of prostatic brachytherapy before argon plasma coagulation for radiation-induced proctitis.Prostatic brachytherapy with permanent seed implants is a recent and safe radiation therapy technique associated with radiation-induced digestive disease.Argon plasma coagulation procedure is a validated modality in the management of haemorrhagic radiation proctitis,which is known to occasionally induce chronic rectal ulcers.We report here an original case report of an acute painful rectal ulcer as a consequence of the combination of shortterm therapy with non-steroidal anti-inflammatory drugs therapy,prostatic brachytherapy with malposition of seed implants and argon plasma coagulation procedure in a patient with haemorrhagic radiation proctitis.The description of this clinical observation is essential to recommend the discontinuation of non-steroidal anti-inflammatory drugs therapy and the control of the position of seed implants in case of prostatic brachytherapy before argon plasma coagulation for radiation-induced proctitis.

关 键 词：Radiation proctitis Prostatic brachytherapy Argon plasma coagulation Non-steroidal anti-inflammatory drugs 

分 类 号：R657.1[医药卫生—外科学]