肠粘连缓解汤治疗急性粘连性肠梗阻的临床观察  

Cl inical Observaion of Changnianlianhuanjie Decoction on Acute Adhesive Intestinal Obstruction

作　　者：刘英巧 罗庆妮 

机构地区：[1]浙江省长兴县中医院,浙江长兴313100

出　　处：《中国中医急症》2015年第4期685-687,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：浙江省药学会医院药学科研专项基金项目(2013ZYY17);浙江省中西医结合学会临床药学科研专项基金项目(2013LYSX015)

摘　　要：目的观察肠粘连缓解汤加减辨治急性粘连性肠梗阻患者的临床疗效。方法将80例粘连性肠梗阻患者按随机数字表法随机分为实验组和对照组,各40例。对照组患者给予石蜡油治疗,实验组患者服用肠粘连缓解汤。观察两组患者治疗后一般临床症状、炎症因子的变化以及临床综合效果。结果治疗后,实验组患者的肛门排气时间、症状消失时间以及气液平消失时间均早于对照组(P<0.05),胃液排出量显著小于对照组(P<0.05);实验组患者的白细胞(WBC)计数、C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)炎症因子的水平均较对照组患者低(P<0.05);实验组患者的总有效率为95.00%,明显高于对照组的72.50%(P<0.05)。结论肠粘连缓解汤加减辨治急性粘连性肠梗肠阻患者,能够显著降低肛门排气时间、症状消失时间以及气液平消失时间,减少胃液排出量,降低炎性因子水平,提高临床治疗效果。Objective: To investigate the clinical efficacy Changnianlianhuanjie Decoction on Acute Adhesive Intestinal Obstruction. Methods: 80 cases were sent randomly divided into experimental group and control group,40 cases in each group. Control group were treated with paraffin treatment,while the experimental group were given Changnianlianhuanjie Decoction. Changes in general clinical symptoms were observed after treatment,changes in inflammatory factors and clinical outcomes compared between two groups of patients. Results: After treatment,patients in the experimental group flatus,time,and liquid level symptoms disappear times less than those of control group;gastric excretion was significantly lower than that of the control group,the index compared with the control group were statistically significant(P < 0.05);WBC count in the experimental group patients,CRP,IL-6,IL-8 levels of inflammatory cytokines were lower than those of control group(P < 0.05);experimental group of patients with a total effective rate of 95.00% compared with the control group of patients(72.50%)(P < 0.05). Conclusion: Treatment adhesions ease decoction of adhesive intestinal obstruction in patients with intestinal barrier,can significantly reduce flatus,time,and liquid level symptoms disappear time,reduce gastric excretion and reduce the level of inflammatory factors,improved clinical outcomes It is a method of treatment in clinical practice is worth.

关 键 词：急性粘连性肠梗肠阻 肠粘连缓解汤 一般临床症状 炎性因子 临床疗效 

分 类 号：R259[医药卫生—中西医结合]