瑞芬太尼或芬太尼复合异丙酚麻醉诱导后气管插管条件及血流动力学的变化  

Comparison of intubating conditions and hemodynamic changes after anesthesia induction with remifentanil or fentanyl and propofol

作　　者：单世民[1] 金玄玉[1] 张晓光[1] 王俊科[1] 

机构地区：[1]中国医科大学附属第一医院麻醉科,辽宁沈阳110001

出　　处：《中国医科大学学报》2004年第1期78-79,85,共3页Journal of China Medical University

摘　　要：目的 :对比不使用肌松剂的情况下 ,瑞芬太尼或芬太尼复合异丙酚麻醉诱导后气管插管条件及血流动力学的变化。方法 :40名病人分为 2组 ,诱导后 2min行气管插管术。分别记录诱导前、诱导后 1min及插管后 2min的平均动脉压 (MAP)和心率 (HR)。插管条件由操作者给予评分。结果 :两组插管成功率均为 10 0 %。瑞芬太尼组插管条件满意率 80 % ,芬太尼 75%。两组诱导后MAP和HR值较基础值均下降 (P <0 .0 5)。插管后两组间的MAP值差异有统计学意义 (P <0 .0 5)。结论 :瑞芬太尼复合异丙酚麻醉诱导取得了同芬太尼复合异丙酚麻醉诱导一样良好的插管条件 。Objective: To compare and assess the intubating conditi on s and hemodynamic changes after anesthesia induction with propofol and remifenta nnil or fentanyl. Methods:Fortypatients wereallocated int o 2 groups.After 2 minutes ,tracheal intubation was performed .We measured meanarterial pressure(MAP) and heart rate(HR) before anesthesia induction, 1 minuteafter induction, and 2 minutes after intubation.Tracheal intubating conditions w ere graded by operater. Results:Intubation was successful in100% patients of both groups.Intubating conditions were regarded as acceptable i n 80% of group I and 75% of group II .The MAP and HR after induction were lowerthan baseline(P<0.05). After intubation, MAP was signifcantly different betw een the 2 groups(P<0.05). Conclusion:The intubating condi tions were similar after anesthesia induction with propofol and remifentanil orfentanyl. Furthermore,the control of cardiovascular responses to tracheal intuba tion with remifenanil is more effective than that with fentanyl.

关 键 词：瑞芬太尼 芬太尼 气管插管条件 血流动力学 

分 类 号：R971[医药卫生—药品]