人皮移植于裸小鼠体上的实验模型  

AN EXPERIMENTAL MODEL OF HUMAN SKIN GRAFTING ON NUDE MOUSE

作　　者：耿建兵[1] 陈起展 许小珊[1] 杨志祥[2] 

机构地区：[1]军事医学科学院毒物药物研究所 [2]军事医学科学院附属医院

出　　处：《军事医学科学院院刊》1989年第3期221-224,共4页Bulletin of the Academy of Military Medical Sciences

摘　　要：本文报道了人皮移植到裸鼠背部的实验模型.通过肉眼及组织学检查,人皮片可活存3个月之久.在皮片移植约1个月后,此模型可用于皮肤药理学和皮肤毒理学的研究.文中简要地讨论了皮片厚度、皮肤创面的固定及包扎和皮片的保护等有关技术问题.An experimental model of human skin grafting on nude mouse back is reported.The grafted skin flaps were examined with naked eyes and histological methods,and might survive for 3 months Approximately 1 month after human skin grafting this model may be used for dermato-pharmacological and dermato-toxicological studies.The thickness of skin flap to be used,the immobilization and bandaging of the skin wound and the protection of the grafted skin flap are discussed briefly.

关 键 词：人皮移植 裸鼠 实验模型 

分 类 号：R965.1[医药卫生—药理学]